CRCGN015_MCF10A.WT.HP_24H:A24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (4-chloro-2-methylphenoxy)acetic acid 11.84 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:A24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.22633
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 4.22531
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 3.00086
TWF2 twinfilin actin binding protein 2 2.70248
MTA1 metastasis associated 1 2.644
PRKCD protein kinase C, delta 2.50842
GHR growth hormone receptor 2.42357
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.17546
LAMA5 laminin, alpha 5 2.08301
LSR lipolysis stimulated lipoprotein receptor 2.03456
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 2.02867
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.01794
CAPN1 calpain 1, (mu/I) large subunit 2.00784
CLBA1 clathrin binding box of aftiphilin containing 1 2.00599
TM7SF2 transmembrane 7 superfamily member 2 2.00584

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -3.96366
GADD45B growth arrest and DNA-damage-inducible, beta -3.91006
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.56629
MSN moesin -3.38536
CBR1 carbonyl reductase 1 -3.16113
CDC20 cell division cycle 20 -2.85887
BAG3 BCL2-associated athanogene 3 -2.75587
HMG20B high mobility group 20B -2.51847
KDM3A lysine (K)-specific demethylase 3A -2.37175
PCNA proliferating cell nuclear antigen -2.32989
ZDHHC6 zinc finger, DHHC-type containing 6 -2.30648
PDLIM1 PDZ and LIM domain 1 -2.23687
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.16459
CBR3 carbonyl reductase 3 -2.1285
FOSL1 FOS-like antigen 1 -2.07369
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.06999