| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | (2s)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid 96.91 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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85 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 6.78404 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.5974 |
| SPAG4 | sperm associated antigen 4 | 3.28237 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.18 |
| STMN2 | stathmin 2 | 3.1684 |
| NSG2 | neuronal vesicle trafficking associated 2 | 2.92465 |
| IL1B | interleukin 1, beta | 2.63622 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.57959 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 2.53508 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.50424 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 | 2.49248 |
| SYN1 | synapsin I | 2.47326 |
| SNAP91 | synaptosomal-associated protein, 91kDa | 2.45006 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.4491 |
| SNCB | synuclein, beta | 2.43714 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.40608 |
| RUNDC3A | RUN domain containing 3A | 2.40527 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.36029 |
| BEX2 | brain expressed X-linked 2 | 2.34268 |
| CAPN10 | calpain 10 | 2.31737 |
| LGI1 | leucine-rich, glioma inactivated 1 | 2.30654 |
| SCAMP5 | secretory carrier membrane protein 5 | 2.28064 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit | 2.26673 |
| NEFH | neurofilament, heavy polypeptide | 2.25185 |
| UPP1 | uridine phosphorylase 1 | 2.24763 |
| IL4R | interleukin 4 receptor | 2.24215 |
| HPCA | hippocalcin | 2.22988 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 2.22723 |
| SQOR | sulfide quinone oxidoreductase | 2.22721 |
| MELK | maternal embryonic leucine zipper kinase | 2.22011 |
| PDYN | prodynorphin | 2.21011 |
| PDLIM1 | PDZ and LIM domain 1 | 2.19644 |
| SYT1 | synaptotagmin I | 2.19322 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 2.14229 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 2.12906 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 | 2.12517 |
| INA | internexin neuronal intermediate filament protein, alpha | 2.08822 |
| ACTL6B | actin-like 6B | 2.06865 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 2.05495 |
| VSNL1 | visinin-like 1 | 2.0544 |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 2.04423 |
| EGF | epidermal growth factor | 2.03565 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 2.01047 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 2.00985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCCB | propionyl CoA carboxylase, beta polypeptide | -6.01406 |
| MSMO1 | methylsterol monooxygenase 1 | -4.75044 |
| ATF5 | activating transcription factor 5 | -4.44445 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.22889 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -4.09722 |
| PCNA | proliferating cell nuclear antigen | -3.74741 |
| NLRP4 | NLR family, pyrin domain containing 4 | -3.58669 |
| PRPF4 | pre-mRNA processing factor 4 | -3.50196 |
| VAT1 | vesicle amine transport 1 | -3.23708 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -3.18784 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.92397 |
| PCDHB16 | protocadherin beta 16 | -2.88138 |
| LDHD | lactate dehydrogenase D | -2.81159 |
| CCDC86 | coiled-coil domain containing 86 | -2.76226 |
| THAP11 | THAP domain containing 11 | -2.72896 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -2.69689 |
| RYR1 | ryanodine receptor 1 (skeletal) | -2.50231 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -2.49488 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.47379 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -2.36406 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.36268 |
| ABITRAM | actin binding transcription modulator | -2.28405 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.25053 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -2.23639 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.22011 |
| CHPT1 | choline phosphotransferase 1 | -2.21083 |
| RAD51C | RAD51 paralog C | -2.20061 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.19476 |
| USP6 | ubiquitin specific peptidase 6 | -2.16654 |
| E2F6 | E2F transcription factor 6 | -2.15853 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -2.1522 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -2.14485 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.12932 |
| HLTF | helicase-like transcription factor | -2.11753 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -2.08692 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -2.06604 |
| CLTC | clathrin, heavy chain (Hc) | -2.05613 |
| CAPNS1 | calpain, small subunit 1 | -2.05262 |
| DHCR7 | 7-dehydrocholesterol reductase | -2.02242 |
| SESN1 | sestrin 1 | -2.00615 |
| KRT10 | keratin 10, type I | -2.00372 |
