CRCGN015_MCF10A.WT.HP_24H:B09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (2s)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid 10.77 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.96386
INTS3 integrator complex subunit 3 3.79434
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.34822
STAP2 signal transducing adaptor family member 2 3.17204
ATP11B ATPase, class VI, type 11B 2.57317
FZD10 frizzled class receptor 10 2.49519
EPN2 epsin 2 2.44175
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.26268
EED embryonic ectoderm development 2.25298
WIF1 WNT inhibitory factor 1 2.11022
STK10 serine/threonine kinase 10 2.10276
PIH1D1 PIH1 domain containing 1 2.05341
SPAG4 sperm associated antigen 4 2.03483
MCUR1 mitochondrial calcium uniporter regulator 1 2.02581

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.37328
NUP85 nucleoporin 85kDa -4.18116
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.82115
MRPL58 mitochondrial ribosomal protein L58 -3.40292
PCCB propionyl CoA carboxylase, beta polypeptide -3.35178
CDK4 cyclin-dependent kinase 4 -3.21554
HMG20B high mobility group 20B -3.19517
ZDHHC6 zinc finger, DHHC-type containing 6 -3.09362
SLC35B1 solute carrier family 35, member B1 -2.9579
KCTD2 potassium channel tetramerization domain containing 2 -2.76457
ATP5PD ATP synthase peripheral stalk subunit d -2.64476
SUMO4 small ubiquitin-like modifier 4 -2.55157
STXBP2 syntaxin binding protein 2 -2.50917
SAP30BP SAP30 binding protein -2.46196
MRPS7 mitochondrial ribosomal protein S7 -2.43409
GDF15 growth differentiation factor 15 -2.27397
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.18958
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.1767
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.12506
JPT1 Jupiter microtubule associated homolog 1 -2.0692
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.03577