CRCGN015_MCF10A.WT.HP_24H:B13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hp163 perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 4.05152
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.92527
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.03015
HMOX1 heme oxygenase 1 2.89892
CXCL2 chemokine (C-X-C motif) ligand 2 2.71401
MAP7 microtubule-associated protein 7 2.64516
ADGRE5 adhesion G protein-coupled receptor E5 2.60442
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.5499
PPARG peroxisome proliferator-activated receptor gamma 2.48544
EAPP E2F-associated phosphoprotein 2.39736
RTN2 reticulon 2 2.3144
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.21388
PKN1 protein kinase N1 2.16598
LAP3 leucine aminopeptidase 3 2.15804
RAP1GAP RAP1 GTPase activating protein 2.14786
PRR7 proline rich 7 (synaptic) 2.14762
SCGB2A1 secretoglobin, family 2A, member 1 2.13024
TXNRD1 thioredoxin reductase 1 2.09978
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.00591

decreased expression

Symbol Name Standardized Value
UBE3C ubiquitin protein ligase E3C -4.31873
MSMO1 methylsterol monooxygenase 1 -3.819
KIF14 kinesin family member 14 -3.40631
CD81 CD81 molecule -3.2706
ALDOC aldolase C, fructose-bisphosphate -3.25955
INSIG1 insulin induced gene 1 -3.22577
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.62939
RPA3 replication protein A3, 14kDa -2.28573
RRAGA Ras-related GTP binding A -2.23496
PRCP prolylcarboxypeptidase (angiotensinase C) -2.20302
CREB1 cAMP responsive element binding protein 1 -2.19955
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.09305
CALCB calcitonin-related polypeptide beta -2.08966