CRCGN015_MCF10A.WT.HP_24H:B14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hp163 perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBX2 T-box 2 4.57381
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 4.30376
SYNE2 spectrin repeat containing, nuclear envelope 2 4.19291
CDCA4 cell division cycle associated 4 3.77652
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.21645
CCNA1 cyclin A1 3.1931
MELK maternal embryonic leucine zipper kinase 2.52258
TIMP2 TIMP metallopeptidase inhibitor 2 2.51117
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.18827
CDH5 cadherin 5, type 2 (vascular endothelium) 2.13076
TXNL4B thioredoxin-like 4B 2.00583

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -4.02597
COG2 component of oligomeric golgi complex 2 -3.18843
TM9SF2 transmembrane 9 superfamily member 2 -3.04397
DCTD dCMP deaminase -2.72107
BASP1 brain abundant, membrane attached signal protein 1 -2.42252
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.34592
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.28848
EREG epiregulin -2.11713
CD81 CD81 molecule -2.11462