CRCGN015_MCF10A.WT.HP_24H:B15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hp163 perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EAPP E2F-associated phosphoprotein 4.68595
SNAP25 synaptosomal-associated protein, 25kDa 3.87029
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.85363
SPTSSA serine palmitoyltransferase, small subunit A 2.83635
COMP cartilage oligomeric matrix protein 2.72803
TXNRD1 thioredoxin reductase 1 2.59986
TBX2 T-box 2 2.54628
KDM5A lysine (K)-specific demethylase 5A 2.48009
VGLL4 vestigial-like family member 4 2.34593
LGMN legumain 2.33543
CCL2 chemokine (C-C motif) ligand 2 2.30804
MCUR1 mitochondrial calcium uniporter regulator 1 2.30778
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.23143
STMN2 stathmin 2 2.05563
SPAG4 sperm associated antigen 4 2.05174
AGR2 anterior gradient 2 2.01682

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -4.18249
PCNA proliferating cell nuclear antigen -4.12784
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.30271
CRTAP cartilage associated protein -2.88939
TUBB6 tubulin, beta 6 class V -2.64181
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.55776
KLRC3 killer cell lectin-like receptor subfamily C, member 3 -2.33365
TLK2 tousled-like kinase 2 -2.24515
KLRC1 killer cell lectin-like receptor subfamily C, member 1 -2.15608
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -2.0589
CST8 cystatin 8 (cystatin-related epididymal specific) -2.02289
TMEM230 transmembrane protein 230 -2.02176