CRCGN015_MCF10A.WT.HP_24H:B16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description beta-naphthoflavone 100.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TIAM1 T-cell lymphoma invasion and metastasis 1 3.76138
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.53985
ZNF586 zinc finger protein 586 3.19768
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.02034
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.98962
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.94906
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.42628
SNX11 sorting nexin 11 2.40402
FGFR4 fibroblast growth factor receptor 4 2.38142
PTX3 pentraxin 3, long 2.12746
ZNF587 zinc finger protein 587 2.11324
CDC25B cell division cycle 25B 2.03297
ZNF587B zinc finger protein 587B 2.02117

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -4.27234
LAP3 leucine aminopeptidase 3 -3.7015
HMG20B high mobility group 20B -3.5515
TSPAN4 tetraspanin 4 -3.17642
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.7339
MSMO1 methylsterol monooxygenase 1 -2.44122
CD81 CD81 molecule -2.36413
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.33019
DUSP14 dual specificity phosphatase 14 -2.04257