| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenz(a,h)anthracene 32.86 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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90 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 6.4109 |
| RAB21 | RAB21, member RAS oncogene family | 5.062 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.50808 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 3.47495 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 3.45945 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.38678 |
| ZFC3H1 | zinc finger, C3H1-type containing | 3.33245 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 3.24215 |
| MTA2 | metastasis associated 1 family, member 2 | 3.23525 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.04657 |
| NUTF2 | nuclear transport factor 2 | 3.02145 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 2.8564 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.84185 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.79715 |
| NISCH | nischarin | 2.6934 |
| IL1B | interleukin 1, beta | 2.68622 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.68178 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 2.65427 |
| CCNL1 | cyclin L1 | 2.61005 |
| TXNL4B | thioredoxin-like 4B | 2.6013 |
| PCDHB11 | protocadherin beta 11 | 2.55276 |
| CDC25B | cell division cycle 25B | 2.5205 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | 2.4738 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) | 2.4498 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 2.4419 |
| STRN3 | striatin, calmodulin binding protein 3 | 2.41057 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.38475 |
| ZC3H4 | zinc finger CCCH-type containing 4 | 2.38445 |
| MDM4 | MDM4, p53 regulator | 2.31135 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.3024 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | 2.2827 |
| ITGA7 | integrin, alpha 7 | 2.2746 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 | 2.25835 |
| SIRAL2 | SIR2 antiphage like 2 | 2.23765 |
| RIN1 | Ras and Rab interactor 1 | 2.23645 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | 2.229 |
| ABHD3 | abhydrolase domain containing 3 | 2.2078 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.1865 |
| HEG1 | heart development protein with EGF-like domains 1 | 2.15095 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.1369 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.1347 |
| WDR4 | WD repeat domain 4 | 2.10515 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.0995 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 2.0592 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 2.03285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PRPF4 | pre-mRNA processing factor 4 | -5.3064 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -5.03752 |
| HMG20B | high mobility group 20B | -4.97145 |
| CCNB1 | cyclin B1 | -4.8825 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -4.79665 |
| FBXO21 | F-box protein 21 | -4.71195 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -4.04145 |
| COPS7A | COP9 signalosome subunit 7A | -3.83555 |
| TAC4 | tachykinin 4 (hemokinin) | -3.4556 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.9449 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -2.85 |
| CD81 | CD81 molecule | -2.8089 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.7711 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -2.64545 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | -2.6198 |
| TNPO1 | transportin 1 | -2.61965 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | -2.6103 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -2.5968 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | -2.59427 |
| MALT1 | MALT1 paracaspase | -2.59298 |
| RGS2 | regulator of G-protein signaling 2 | -2.4539 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | -2.34255 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -2.2862 |
| GPN3 | GPN-loop GTPase 3 | -2.28295 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 | -2.26712 |
| CD320 | CD320 molecule | -2.26265 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -2.23757 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.2206 |
| SRFBP1 | serum response factor binding protein 1 | -2.1548 |
| SREK1IP1 | SREK1-interacting protein 1 | -2.11345 |
| ARB2A | ARB2 cotranscriptional regulator A | -2.11235 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -2.1076 |
| PHB2 | prohibitin 2 | -2.0973 |
| MLF2 | myeloid leukemia factor 2 | -2.0946 |
| TBC1D4 | TBC1 domain family, member 4 | -2.09055 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | -2.0788 |
| METTL9 | methyltransferase like 9 | -2.07065 |
| COTL1 | coactosin-like F-actin binding protein 1 | -2.06965 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -2.05905 |
| KIF1B | kinesin family member 1B | -2.0508 |
| DIABLO | diablo, IAP-binding mitochondrial protein | -2.04785 |
| ADGRE2 | adhesion G protein-coupled receptor E2 | -2.0478 |
| BCAP31 | B-cell receptor-associated protein 31 | -2.0375 |
| STX8 | syntaxin 8 | -2.03565 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -2.0156 |
