CRCGN015_MCF10A.WT.HP_24H:B22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 5-(4-{2-[methyl(2-pyridinyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione 104.84 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

511 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 9.2852
GLRX glutaredoxin (thioltransferase) 7.1243
CHIC2 cysteine-rich hydrophobic domain 2 6.98442
COMP cartilage oligomeric matrix protein 6.8208
TRIB1 tribbles pseudokinase 1 6.6663
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.35983
WIF1 WNT inhibitory factor 1 6.34902
AARS1 alanyl-tRNA synthetase 1 6.01915
EGR1 early growth response 1 5.97965
PTPN1 protein tyrosine phosphatase, non-receptor type 1 5.82753
FOSL1 FOS-like antigen 1 5.72144
SQOR sulfide quinone oxidoreductase 5.69898
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.28842
KCTD5 potassium channel tetramerization domain containing 5 5.22895
TRIB3 tribbles pseudokinase 3 5.07588
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.98046
GARS1 glycyl-tRNA synthetase 1 4.83285
CCNA1 cyclin A1 4.80132
SYNGAP1 synaptic Ras GTPase activating protein 1 4.71444
STXBP1 syntaxin binding protein 1 4.60991
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.54543
HMGA2 high mobility group AT-hook 2 4.51749
ASNS asparagine synthetase (glutamine-hydrolyzing) 4.51079
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.41233
IER3 immediate early response 3 4.3826
CARS1 cysteinyl-tRNA synthetase 1 4.36603
FOS FBJ murine osteosarcoma viral oncogene homolog 4.34673
TXNRD1 thioredoxin reductase 1 4.30443
PYCR1 pyrroline-5-carboxylate reductase 1 4.18886
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.14077
DUSP6 dual specificity phosphatase 6 4.07825
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 4.06312
FHL2 four and a half LIM domains 2 3.94985
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.89997
PSAT1 phosphoserine aminotransferase 1 3.75941
MACF1 microtubule-actin crosslinking factor 1 3.75932
UGDH UDP-glucose 6-dehydrogenase 3.74578
STX1A syntaxin 1A (brain) 3.70169
PYGB phosphorylase, glycogen; brain 3.64688
VEGFC vascular endothelial growth factor C 3.62948
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 3.61381
LARP6 La ribonucleoprotein domain family, member 6 3.48362
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 3.46455
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 3.45967
ATF4 activating transcription factor 4 3.37853
CCL2 chemokine (C-C motif) ligand 2 3.35383
DUSP4 dual specificity phosphatase 4 3.33971
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 3.31735
INPP1 inositol polyphosphate-1-phosphatase 3.29949
PHGDH phosphoglycerate dehydrogenase 3.28806
CAMTA2 calmodulin binding transcription activator 2 3.27932
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 3.26812
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.24035
YARS1 tyrosyl-tRNA synthetase 1 3.22589
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 3.21503
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 3.21257
LIF leukemia inhibitory factor 3.20731
EPHA2 EPH receptor A2 3.20359
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 3.20106
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 3.12727
LRP10 low density lipoprotein receptor-related protein 10 3.11281
G0S2 G0/G1 switch 2 3.10961
HBEGF heparin-binding EGF-like growth factor 3.10464
CSNK1E casein kinase 1, epsilon 3.07976
PLEC plectin 3.07008
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.04052
RGS2 regulator of G-protein signaling 2 2.99604
EGR3 early growth response 3 2.99586
PNKP polynucleotide kinase 3'-phosphatase 2.96181
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.9508
HAS2 hyaluronan synthase 2 2.91938
NCOA3 nuclear receptor coactivator 3 2.90962
TWF2 twinfilin actin binding protein 2 2.9094
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.90157
GTPBP2 GTP binding protein 2 2.88641
SDC4 syndecan 4 2.86297
IGFBP1 insulin-like growth factor binding protein 1 2.86293
LOC128125814 uncharacterized LOC128125814 2.86191
HMGA1 high mobility group AT-hook 1 2.84596
LAMC2 laminin, gamma 2 2.83963
KIF5C kinesin family member 5C 2.83725
NPC1 Niemann-Pick disease, type C1 2.81773
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.81645
UPP1 uridine phosphorylase 1 2.77391
CD44 CD44 molecule (Indian blood group) 2.77376
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.77282
NUCB2 nucleobindin 2 2.74507
SPRY4 sprouty homolog 4 (Drosophila) 2.7156
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.6843
KDM7A lysine (K)-specific demethylase 7A 2.67937
BCAR3 breast cancer anti-estrogen resistance 3 2.66799
USO1 USO1 vesicle transport factor 2.65336
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.63019
KDM5C lysine (K)-specific demethylase 5C 2.62704
TARS1 threonyl-tRNA synthetase 1 2.61688
MAN2A1 mannosidase, alpha, class 2A, member 1 2.61643
MEF2A myocyte enhancer factor 2A 2.61606
FNDC4 fibronectin type III domain containing 4 2.61082
ZFP36 ZFP36 ring finger protein 2.61035
CALU calumenin 2.5905
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.59036
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.58592
MARS1 methionyl-tRNA synthetase 1 2.57738
CDK17 cyclin-dependent kinase 17 2.57616
GOLGA3 golgin A3 2.56963
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.56877
GPC1 glypican 1 2.56853
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.56698
GCLM glutamate-cysteine ligase, modifier subunit 2.56041
BCL10 B-cell CLL/lymphoma 10 2.55604
FAM131A family with sequence similarity 131, member A 2.55415
PFDN2 prefoldin subunit 2 2.55187
RRBP1 ribosome binding protein 1 2.54815
GRB10 growth factor receptor-bound protein 10 2.5409
DUSP5 dual specificity phosphatase 5 2.53003
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 2.51308
MANF mesencephalic astrocyte-derived neurotrophic factor 2.50988
NDEL1 nudE neurodevelopment protein 1-like 1 2.50416
LHFPL2 lipoma HMGIC fusion partner-like 2 2.50358
ITCH itchy E3 ubiquitin protein ligase 2.49849
KCMF1 potassium channel modulatory factor 1 2.49686
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.47767
ATXN2 ataxin 2 2.47571
ANKRD11 ankyrin repeat domain 11 2.47428
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 2.46907
MBD5 methyl-CpG binding domain protein 5 2.46448
IER2 immediate early response 2 2.4392
FGD1 FYVE, RhoGEF and PH domain containing 1 2.43865
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.4127
ITGA6 integrin, alpha 6 2.4075
PSD3 pleckstrin and Sec7 domain containing 3 2.40356
CDCP1 CUB domain containing protein 1 2.39741
F7 coagulation factor VII (serum prothrombin conversion accelerator) 2.38739
SARS1 seryl-tRNA synthetase 1 2.37503
ACVR1 activin A receptor, type I 2.36299
RTN4 reticulon 4 2.35461
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 2.34635
RAB38 RAB38, member RAS oncogene family 2.34077
ADAT1 adenosine deaminase, tRNA-specific 1 2.33285
BMAL2 basic helix-loop-helix ARNT like 2 2.32523
GOLT1A golgi transport 1A 2.3198
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 2.31927
DVL1 dishevelled segment polarity protein 1 2.31782
PLK3 polo-like kinase 3 2.31567
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.31537
VAT1 vesicle amine transport 1 2.30907
INHBA inhibin, beta A 2.30821
NPAS2 neuronal PAS domain protein 2 2.30181
FLNB filamin B, beta 2.29816
ANO1 anoctamin 1, calcium activated chloride channel 2.29811
FIP1L1 factor interacting with PAPOLA and CPSF1 2.29719
MAP3K20 mitogen-activated protein kinase kinase kinase 20 2.29167
TSPAN5 tetraspanin 5 2.29129
KMT5A lysine methyltransferase 5A 2.27242
INHBE inhibin, beta E 2.26069
GARRE1 granule associated Rac and RHOG effector 1 2.26012
UBA1 ubiquitin-like modifier activating enzyme 1 2.25271
FN1 fibronectin 1 2.24601
ATOSB atos homolog B 2.24257
COPB1 coatomer protein complex, subunit beta 1 2.24044
FURIN furin (paired basic amino acid cleaving enzyme) 2.23467
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 2.22218
IARS1 isoleucyl-tRNA synthetase 1 2.22118
NT5E 5'-nucleotidase, ecto (CD73) 2.21094
ARL4D ADP-ribosylation factor-like 4D 2.20943
SPHK1 sphingosine kinase 1 2.20629
XPOT exportin, tRNA 2.20416
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 2.20024
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.19506
FERMT2 fermitin family member 2 2.19339
S100P S100 calcium binding protein P 2.19034
EPN2 epsin 2 2.18538
H1-0 H1.0 linker histone 2.17952
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.17662
PORCN porcupine homolog (Drosophila) 2.17498
UNC5B unc-5 homolog B (C. elegans) 2.17441
AKAP17A A kinase (PRKA) anchor protein 17A 2.17089
GALE UDP-galactose-4-epimerase 2.16918
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.15936
NRDC nardilysin convertase 2.15623
ITPRID2 ITPR interacting domain containing 2 2.15245
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.15099
MMP1 matrix metallopeptidase 1 2.1501
STAU1 staufen double-stranded RNA binding protein 1 2.14781
MYH9 myosin, heavy chain 9, non-muscle 2.14235
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 2.13827
CDK5RAP2 CDK5 regulatory subunit associated protein 2 2.13536
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.13448
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.13336
PRRX2 paired related homeobox 2 2.13242
ERGIC2 ERGIC and golgi 2 2.12968
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.12428
SOWAHC sosondowah ankyrin repeat domain family member C 2.12322
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 2.12199
POPDC3 popeye domain containing 3 2.11116
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 2.1066
ITGA10 integrin, alpha 10 2.09589
KRT6B keratin 6B, type II 2.09356
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 2.09339
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.08328
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.07509
MARK4 MAP/microtubule affinity-regulating kinase 4 2.07065
STX4 syntaxin 4 2.06574
TMEM184B transmembrane protein 184B 2.06172
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 2.0615
EREG epiregulin 2.06013
TERF2IP telomeric repeat binding factor 2, interacting protein 2.04687
TSG101 tumor susceptibility 101 2.04057
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.03831
FAM50A family with sequence similarity 50, member A 2.03478
MID1IP1 MID1 interacting protein 1 2.03353
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.03139
KIF13B kinesin family member 13B 2.02693
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.02614
CCN2 cellular communication network factor 2 2.02335
TFPI2 tissue factor pathway inhibitor 2 2.02266
F3 coagulation factor III (thromboplastin, tissue factor) 2.0209
FKBP14 FK506 binding protein 14, 22 kDa 2.0162
CKAP5 cytoskeleton associated protein 5 2.01601
PTHLH parathyroid hormone-like hormone 2.01464
TPBG trophoblast glycoprotein 2.01083
TPM4 tropomyosin 4 2.00965
GSTO1 glutathione S-transferase omega 1 2.00816

decreased expression

Symbol Name Standardized Value
HOXA5 homeobox A5 -6.36446
STMN1 stathmin 1 -5.70779
ADRB2 adrenoceptor beta 2, surface -5.44933
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.24201
ALDOC aldolase C, fructose-bisphosphate -5.00467
PRR15L proline rich 15-like -4.90468
UFM1 ubiquitin-fold modifier 1 -4.88691
MCM3 minichromosome maintenance complex component 3 -4.26426
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.22646
TMEM50A transmembrane protein 50A -4.21794
ATF5 activating transcription factor 5 -4.21338
COG7 component of oligomeric golgi complex 7 -4.04552
SESN1 sestrin 1 -4.03074
ADI1 acireductone dioxygenase 1 -3.70718
TMEM109 transmembrane protein 109 -3.70248
GINS3 GINS complex subunit 3 (Psf3 homolog) -3.69551
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.68007
TP53 tumor protein p53 -3.67396
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -3.55108
NUP133 nucleoporin 133kDa -3.48248
SCGB1D1 secretoglobin, family 1D, member 1 -3.47187
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.38143
GTPBP8 GTP-binding protein 8 (putative) -3.30076
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.28225
COMMD9 COMM domain containing 9 -3.27849
MXI1 MAX interactor 1, dimerization protein -3.21929
FAIM Fas apoptotic inhibitory molecule -3.21785
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.18757
MEPCE methylphosphate capping enzyme -3.18748
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -3.18509
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) -3.16914
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.15521
ZSCAN5A zinc finger and SCAN domain containing 5A -3.07588
ZDHHC6 zinc finger, DHHC-type containing 6 -3.07024
PCCB propionyl CoA carboxylase, beta polypeptide -3.06561
TMEM14A transmembrane protein 14A -3.06474
EIF5 eukaryotic translation initiation factor 5 -3.02184
BIRC5 baculoviral IAP repeat containing 5 -3.02133
CROT carnitine O-octanoyltransferase -3.01082
CDC45 cell division cycle 45 -3.00973
NXF2B nuclear RNA export factor 2B -3.00367
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.0035
HOXA4 homeobox A4 -2.93321
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.90625
USP19 ubiquitin specific peptidase 19 -2.88224
FAM13B family with sequence similarity 13, member B -2.88181
RANBP10 RAN binding protein 10 -2.87066
KDM3B lysine (K)-specific demethylase 3B -2.86921
YJU2 YJU2 splicing factor homolog -2.86502
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -2.86125
CD320 CD320 molecule -2.85869
SETMAR SET domain and mariner transposase fusion gene -2.85668
ACOT2 acyl-CoA thioesterase 2 -2.85215
THAP11 THAP domain containing 11 -2.84724
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -2.84364
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.84342
BAG1 BCL2-associated athanogene -2.82567
NUBP2 nucleotide binding protein 2 -2.82356
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.81965
CYCS cytochrome c, somatic -2.81473
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.80744
PFKM phosphofructokinase, muscle -2.80594
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.80437
PSRC1 proline/serine-rich coiled-coil 1 -2.80433
ZNF45 zinc finger protein 45 -2.80168
ZW10 zw10 kinetochore protein -2.78065
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.77164
ZNF200 zinc finger protein 200 -2.76267
CTSS cathepsin S -2.76114
KIF20A kinesin family member 20A -2.76033
TMCO1 transmembrane and coiled-coil domains 1 -2.74638
CCL4 chemokine (C-C motif) ligand 4 -2.73618
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -2.72935
GZMM granzyme M (lymphocyte met-ase 1) -2.72509
VAV3 vav 3 guanine nucleotide exchange factor -2.7164
MCMBP minichromosome maintenance complex binding protein -2.71527
NLRP2B NLR family pyrin domain containing 2B -2.68555
HIGD1B HIG1 hypoxia inducible domain family, member 1B -2.65205
BPHL biphenyl hydrolase-like (serine hydrolase) -2.64545
ZNF544 zinc finger protein 544 -2.64162
HIRIP3 HIRA interacting protein 3 -2.62061
GCDH glutaryl-CoA dehydrogenase -2.61925
VSIG10 V-set and immunoglobulin domain containing 10 -2.61831
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -2.61608
COG2 component of oligomeric golgi complex 2 -2.61266
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.61082
MEIS1 Meis homeobox 1 -2.60846
BTN3A1 butyrophilin, subfamily 3, member A1 -2.60688
PEPD peptidase D -2.60248
TUBGCP5 tubulin, gamma complex associated protein 5 -2.5961
SLC35A5 solute carrier family 35, member A5 -2.59355
TSPAN6 tetraspanin 6 -2.5917
PARP1 poly (ADP-ribose) polymerase 1 -2.58903
DCK deoxycytidine kinase -2.57015
C2CD5 C2 calcium-dependent domain containing 5 -2.56962
KAT2A K(lysine) acetyltransferase 2A -2.56905
ARRB1 arrestin, beta 1 -2.56801
NUP160 nucleoporin 160kDa -2.55503
TCEA2 transcription elongation factor A (SII), 2 -2.54526
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) -2.53107
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.52998
BID BH3 interacting domain death agonist -2.51147
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.51014
RPUSD2 RNA pseudouridylate synthase domain containing 2 -2.50906
RTP4 receptor (chemosensory) transporter protein 4 -2.49817
ELAC2 elaC ribonuclease Z 2 -2.49683
HDAC3 histone deacetylase 3 -2.49654
PNPO pyridoxamine 5'-phosphate oxidase -2.49538
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.48677
ICOS inducible T-cell co-stimulator -2.48022
ZNF551 zinc finger protein 551 -2.47745
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.47322
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.47176
RFC3 replication factor C (activator 1) 3, 38kDa -2.47032
KRT13 keratin 13, type I -2.46977
MRLN myoregulin -2.46838
MTA2 metastasis associated 1 family, member 2 -2.4538
GDE1 glycerophosphodiester phosphodiesterase 1 -2.44276
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.43931
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -2.43787
MAGEA10 melanoma antigen family A10 -2.43515
GHR growth hormone receptor -2.4298
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 -2.42797
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.42557
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.42417
TOE1 target of EGR1, member 1 (nuclear) -2.4225
JADE2 jade family PHD finger 2 -2.41663
C1QBP complement component 1, q subcomponent binding protein -2.41423
BTN3A2 butyrophilin, subfamily 3, member A2 -2.40926
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.40514
UNC119B unc-119 homolog B (C. elegans) -2.3842
SPIN2B spindlin family, member 2B -2.38265
PRPF31 pre-mRNA processing factor 31 -2.38096
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.38071
R3HCC1 R3H domain and coiled-coil containing 1 -2.37333
ZNF318 zinc finger protein 318 -2.37137
TMBIM4 transmembrane BAX inhibitor motif containing 4 -2.36553
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.36029
ZNF394 zinc finger protein 394 -2.35467
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.35162
MYLIP myosin regulatory light chain interacting protein -2.35067
WDR37 WD repeat domain 37 -2.34434
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.34311
TSPAN3 tetraspanin 3 -2.33456
METTL17 methyltransferase like 17 -2.3329
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.32906
EVI2B ecotropic viral integration site 2B -2.32754
FN3KRP fructosamine 3 kinase related protein -2.32742
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.32524
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -2.31964
ZSCAN32 zinc finger and SCAN domain containing 32 -2.31389
BPIFA1 BPI fold containing family A, member 1 -2.31301
BLCAP bladder cancer associated protein -2.31252
ATG3 autophagy related 3 -2.31188
ERI2 ERI1 exoribonuclease family member 2 -2.30673
TXNL4B thioredoxin-like 4B -2.30615
FAM200C family with sequence similarity 200 member C -2.30448
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -2.30443
TRIM68 tripartite motif containing 68 -2.29872
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.29475
POLR1D polymerase (RNA) I polypeptide D, 16kDa -2.29179
ACHE acetylcholinesterase (Yt blood group) -2.29165
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -2.28708
MTMR14 myotubularin related protein 14 -2.28422
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -2.27844
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.27411
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.27369
ZNF227 zinc finger protein 227 -2.27137
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -2.27086
COQ3 coenzyme Q3 methyltransferase -2.26951
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.26913
ZNF263 zinc finger protein 263 -2.2677
TCEAL1 transcription elongation factor A (SII)-like 1 -2.26679
TOR1AIP2 torsin A interacting protein 2 -2.265
PRMT7 protein arginine methyltransferase 7 -2.26028
S100A8 S100 calcium binding protein A8 -2.25835
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.24733
TMEM184C transmembrane protein 184C -2.24221
TNF tumor necrosis factor -2.23711
ZDHHC3 zinc finger, DHHC-type containing 3 -2.23492
GIMAP4 GTPase, IMAP family member 4 -2.2337
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -2.2301
MRPL30 mitochondrial ribosomal protein L30 -2.22934
CDC25C cell division cycle 25C -2.22928
SRRT serrate, RNA effector molecule -2.22906
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.22399
ZNF267 zinc finger protein 267 -2.22257
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -2.21386
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.21299
CCNB2 cyclin B2 -2.20954
JRK Jrk homolog (mouse) -2.20843
SRSF3 serine/arginine-rich splicing factor 3 -2.20554
ATRIP ATR interacting protein -2.20301
MCM10 minichromosome maintenance complex component 10 -2.19531
HOXB5 homeobox B5 -2.19461
ZNF669 zinc finger protein 669 -2.19043
PTGER4 prostaglandin E receptor 4 (subtype EP4) -2.19003
PPP4R3B protein phosphatase 4 regulatory subunit 3B -2.18586
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -2.18571
ABHD14A abhydrolase domain containing 14A -2.18549
DHFR dihydrofolate reductase -2.18214
ZBTB24 zinc finger and BTB domain containing 24 -2.18137
RAD51AP1 RAD51 associated protein 1 -2.17984
GPR65 G protein-coupled receptor 65 -2.17914
TFDP1 transcription factor Dp-1 -2.17641
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -2.17439
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.17436
ZNF16 zinc finger protein 16 -2.17417
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -2.17152
PALB2 partner and localizer of BRCA2 -2.16056
PHKB phosphorylase kinase, beta -2.15365
SRSF2 serine/arginine-rich splicing factor 2 -2.1531
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.15241
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -2.1519
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.15035
FAM117A family with sequence similarity 117, member A -2.14861
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -2.14733
SSX5 synovial sarcoma, X breakpoint 5 -2.14422
FAM32A family with sequence similarity 32, member A -2.1437
VCX3A variable charge, X-linked 3A -2.1399
RNASE7 ribonuclease, RNase A family, 7 -2.13751
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -2.13697
SP2 Sp2 transcription factor -2.13266
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -2.13229
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.13201
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.12794
HADH hydroxyacyl-CoA dehydrogenase -2.12631
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -2.12344
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.12065
NUP85 nucleoporin 85kDa -2.1196
FEN1 flap structure-specific endonuclease 1 -2.11644
ATG4A autophagy related 4A, cysteine peptidase -2.11558
ZNF134 zinc finger protein 134 -2.11461
CYB5RL cytochrome b5 reductase-like -2.11395
TXNDC9 thioredoxin domain containing 9 -2.11376
SH3D19 SH3 domain containing 19 -2.11039
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 -2.10927
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.10577
DNAAF2 dynein, axonemal, assembly factor 2 -2.1048
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.10473
TWNK twinkle mtDNA helicase -2.10412
HEXIM1 hexamethylene bis-acetamide inducible 1 -2.10149
ZNF324B zinc finger protein 324B -2.09938
REPIN1 replication initiator 1 -2.09496
ASTE1 asteroid homolog 1 (Drosophila) -2.0919
NUSAP1 nucleolar and spindle associated protein 1 -2.08805
CD48 CD48 molecule -2.08745
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.08673
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.08173
ZNF180 zinc finger protein 180 -2.07871
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.07566
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.07324
MARCO macrophage receptor with collagenous structure -2.07291
LZTFL1 leucine zipper transcription factor-like 1 -2.07248
CDK4 cyclin-dependent kinase 4 -2.0716
EHMT2 euchromatic histone-lysine N-methyltransferase 2 -2.06618
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.06589
CKAP2 cytoskeleton associated protein 2 -2.0584
NASP nuclear autoantigenic sperm protein (histone-binding) -2.05452
RNF125 ring finger protein 125, E3 ubiquitin protein ligase -2.05119
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -2.04997
FCF1 FCF1 rRNA-processing protein -2.0484
CCL3L3 chemokine (C-C motif) ligand 3-like 3 -2.0446
ODF1 outer dense fiber of sperm tails 1 -2.03887
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -2.03617
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -2.0338
MTRF1 mitochondrial translational release factor 1 -2.03063
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.02857
ERCC6L excision repair cross-complementation group 6-like -2.02633
DENND1C DENN/MADD domain containing 1C -2.02599
DCTN5 dynactin 5 (p25) -2.02262
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.02222
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -2.02196
SP8 Sp8 transcription factor -2.02039
FXN frataxin -2.01874
TUSC2 tumor suppressor candidate 2 -2.01853
PGRMC1 progesterone receptor membrane component 1 -2.01506
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.01292
JPT2 Jupiter microtubule associated homolog 2 -2.01228
SMIM7 small integral membrane protein 7 -2.01137
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 -2.01126
PUS3 pseudouridylate synthase 3 -2.01026
BRCA1 breast cancer 1, early onset -2.00859
LIPT1 lipoyltransferase 1 -2.00759
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.00617
CD180 CD180 molecule -2.00541
CENPU centromere protein U -2.00404
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.00091