CRCGN015_MCF10A.WT.HP_24H:C01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tryptamine 100.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 3.70899
MAMLD1 mastermind-like domain containing 1 3.69157
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 3.61932
SPAG4 sperm associated antigen 4 3.31149
FGFR4 fibroblast growth factor receptor 4 3.24773
COMP cartilage oligomeric matrix protein 2.94906
HLA-DRA major histocompatibility complex, class II, DR alpha 2.78243
CENPE centromere protein E, 312kDa 2.71164
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.68399
INSIG1 insulin induced gene 1 2.63055
MOK MOK protein kinase 2.59151
WIF1 WNT inhibitory factor 1 2.5041
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.43728
CHIC2 cysteine-rich hydrophobic domain 2 2.19461
TRIB3 tribbles pseudokinase 3 2.1655
CRELD2 cysteine-rich with EGF-like domains 2 2.09656

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -4.23098
CHMP4B charged multivesicular body protein 4B -3.80672
PCNA proliferating cell nuclear antigen -3.70069
VDAC1 voltage-dependent anion channel 1 -3.53287
PSIP1 PC4 and SFRS1 interacting protein 1 -3.43208
TP53 tumor protein p53 -3.35923
COPS7A COP9 signalosome subunit 7A -3.0065
MCM3 minichromosome maintenance complex component 3 -3.0054
MTERF3 mitochondrial transcription termination factor 3 -2.94035
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.86496
IFRD2 interferon-related developmental regulator 2 -2.53574
RFC2 replication factor C (activator 1) 2, 40kDa -2.34245
OXA1L oxidase (cytochrome c) assembly 1-like -2.32499
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.29477
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.28475
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.22987
SCYL3 SCY1-like 3 (S. cerevisiae) -2.22298
BAG1 BCL2-associated athanogene -2.07164
KIF20A kinesin family member 20A -2.03525
PSRC1 proline/serine-rich coiled-coil 1 -2.01713
LYPLA1 lysophospholipase I -2.01035