| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tryptamine 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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159 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COMP | cartilage oligomeric matrix protein | 4.76529 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.75824 |
| IL1B | interleukin 1, beta | 4.57305 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.22486 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.75983 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.34788 |
| TENT4A | terminal nucleotidyltransferase 4A | 3.33101 |
| MPC2 | mitochondrial pyruvate carrier 2 | 3.27072 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.21972 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.19122 |
| GRB7 | growth factor receptor-bound protein 7 | 3.02718 |
| GATA2 | GATA binding protein 2 | 3.0208 |
| TDRD12 | tudor domain containing 12 | 2.59759 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 2.59659 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 2.55143 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.54117 |
| MOB3B | MOB kinase activator 3B | 2.47589 |
| ZNF804A | zinc finger protein 804A | 2.43077 |
| ARG2 | arginase 2 | 2.42991 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 2.40106 |
| ANGPTL2 | angiopoietin-like 2 | 2.3747 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.37247 |
| KLF11 | Kruppel-like factor 11 | 2.37106 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 | 2.36394 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 2.35276 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 | 2.34333 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.31845 |
| PLAC1 | placenta-specific 1 | 2.29902 |
| UVRAG | UV radiation resistance associated | 2.29557 |
| SMIM5 | small integral membrane protein 5 | 2.25234 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | 2.24475 |
| DPYD | dihydropyrimidine dehydrogenase | 2.23705 |
| FGF5 | fibroblast growth factor 5 | 2.23478 |
| TESK1 | testis-specific kinase 1 | 2.23359 |
| PPOX | protoporphyrinogen oxidase | 2.22202 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 2.21356 |
| PCLO | piccolo presynaptic cytomatrix protein | 2.21107 |
| SQOR | sulfide quinone oxidoreductase | 2.18793 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.17894 |
| ZNF215 | zinc finger protein 215 | 2.17873 |
| HOXC5 | homeobox C5 | 2.16803 |
| ZMAT5 | zinc finger, matrin-type 5 | 2.16043 |
| KATNIP | katanin interacting protein | 2.15798 |
| NRBP1 | nuclear receptor binding protein 1 | 2.15009 |
| RTN2 | reticulon 2 | 2.14499 |
| ZFHX4 | zinc finger homeobox 4 | 2.14206 |
| PKN1 | protein kinase N1 | 2.13841 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.13811 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.13346 |
| LPAR3 | lysophosphatidic acid receptor 3 | 2.13284 |
| MMP2 | matrix metallopeptidase 2 | 2.12628 |
| SIRT3 | sirtuin 3 | 2.11982 |
| IL25 | interleukin 25 | 2.11739 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 2.11661 |
| KANK3 | KN motif and ankyrin repeat domains 3 | 2.11328 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.11119 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 2.10337 |
| S100A5 | S100 calcium binding protein A5 | 2.10189 |
| WASHC5 | WASH complex subunit 5 | 2.10151 |
| TRIM13 | tripartite motif containing 13 | 2.07923 |
| CAMKV | CaM kinase-like vesicle-associated | 2.0754 |
| THOC6 | THO complex 6 | 2.07085 |
| RBP4 | retinol binding protein 4, plasma | 2.06947 |
| CTBP2 | C-terminal binding protein 2 | 2.06945 |
| EMILIN2 | elastin microfibril interfacer 2 | 2.06505 |
| RTL8A | retrotransposon Gag like 8A | 2.06252 |
| TRIB3 | tribbles pseudokinase 3 | 2.05802 |
| LRRC15 | leucine rich repeat containing 15 | 2.05573 |
| PRDM1 | PR domain containing 1, with ZNF domain | 2.0532 |
| KCNG2 | potassium channel, voltage gated modifier subfamily G, member 2 | 2.04119 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 2.03686 |
| NELL2 | NEL-like 2 (chicken) | 2.03461 |
| TMEM39B | transmembrane protein 39B | 2.03442 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.02933 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase | 2.02516 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.02371 |
| TFCP2 | transcription factor CP2 | 2.02278 |
| SCN2A | sodium channel, voltage gated, type II alpha subunit | 2.00817 |
| C5 | complement component 5 | 2.00682 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.0025 |
| PDE8B | phosphodiesterase 8B | 2.00028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -7.52501 |
| TNIP1 | TNFAIP3 interacting protein 1 | -4.54604 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.21703 |
| MSN | moesin | -3.77228 |
| PRPF4 | pre-mRNA processing factor 4 | -3.75451 |
| THAP11 | THAP domain containing 11 | -3.44885 |
| GOLT1B | golgi transport 1B | -3.44409 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -3.11224 |
| LDHD | lactate dehydrogenase D | -3.0965 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -3.05298 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -3.04294 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.89337 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -2.81198 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -2.68832 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.66675 |
| RPL36AL | ribosomal protein L36a-like | -2.66172 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 | -2.64699 |
| EDF1 | endothelial differentiation-related factor 1 | -2.57575 |
| SRPRB | signal recognition particle receptor, B subunit | -2.54242 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -2.5094 |
| HEATR1 | HEAT repeat containing 1 | -2.46899 |
| YIPF5 | Yip1 domain family, member 5 | -2.46592 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -2.4111 |
| TMEM208 | transmembrane protein 208 | -2.39667 |
| MLEC | malectin | -2.38491 |
| ECD | ecdysoneless homolog (Drosophila) | -2.37953 |
| RPL36 | ribosomal protein L36 | -2.36138 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | -2.35283 |
| KRT10 | keratin 10, type I | -2.34388 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.33814 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -2.32703 |
| MUC7 | mucin 7, secreted | -2.32545 |
| NCK2 | NCK adaptor protein 2 | -2.30845 |
| ERGIC2 | ERGIC and golgi 2 | -2.30635 |
| SRFBP1 | serum response factor binding protein 1 | -2.296 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -2.29453 |
| EMC7 | ER membrane protein complex subunit 7 | -2.29414 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | -2.27068 |
| BST2 | bone marrow stromal cell antigen 2 | -2.26661 |
| PDCD5 | programmed cell death 5 | -2.25663 |
| MRPS33 | mitochondrial ribosomal protein S33 | -2.25348 |
| NNT | nicotinamide nucleotide transhydrogenase | -2.24347 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.22308 |
| ZNF189 | zinc finger protein 189 | -2.21846 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | -2.21437 |
| FASTKD5 | FAST kinase domains 5 | -2.21234 |
| NOL8 | nucleolar protein 8 | -2.20869 |
| FBXW2 | F-box and WD repeat domain containing 2 | -2.19427 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -2.18387 |
| DDX19A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A | -2.17551 |
| ITPRID2 | ITPR interacting domain containing 2 | -2.17332 |
| B2M | beta-2-microglobulin | -2.16359 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.16311 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -2.16235 |
| VDAC1 | voltage-dependent anion channel 1 | -2.16016 |
| KARS1 | lysyl-tRNA synthetase 1 | -2.1551 |
| TDRD7 | tudor domain containing 7 | -2.15403 |
| CLK4 | CDC-like kinase 4 | -2.15212 |
| SCAF8 | SR-related CTD-associated factor 8 | -2.14818 |
| CDK6 | cyclin-dependent kinase 6 | -2.1433 |
| RBM34 | RNA binding motif protein 34 | -2.13782 |
| LOC128125822 | uncharacterized LOC128125822 | -2.1368 |
| ARL10 | ADP-ribosylation factor-like 10 | -2.11296 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -2.11159 |
| METRN | meteorin, glial cell differentiation regulator | -2.09641 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | -2.06759 |
| PHF2 | PHD finger protein 2 | -2.05751 |
| INTS13 | integrator complex subunit 13 | -2.05717 |
| ABITRAM | actin binding transcription modulator | -2.04958 |
| LDHB | lactate dehydrogenase B | -2.0425 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | -2.02113 |
| PRB4 | proline-rich protein BstNI subfamily 4 | -2.01343 |
| PMP2 | peripheral myelin protein 2 | -2.01247 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | -2.00943 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -2.00885 |
| PPP6C | protein phosphatase 6, catalytic subunit | -2.00573 |
| CAPNS1 | calpain, small subunit 1 | -2.00316 |
| SNRPF | small nuclear ribonucleoprotein polypeptide F | -2.00116 |
