CRCGN015_MCF10A.WT.HP_24H:C05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tranilast 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 5.27828
GSTZ1 glutathione S-transferase zeta 1 3.45217
COMP cartilage oligomeric matrix protein 3.37879
TUBB6 tubulin, beta 6 class V 3.22243
CIAO3 cytosolic iron-sulfur assembly component 3 2.56904
RGS2 regulator of G-protein signaling 2 2.41785
MUC1 mucin 1, cell surface associated 2.41378
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.40469
KLHDC2 kelch domain containing 2 2.15104
RPL39L ribosomal protein L39-like 2.15096
PDLIM1 PDZ and LIM domain 1 2.12138
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.11914
S100A4 S100 calcium binding protein A4 2.10177
ECM1 extracellular matrix protein 1 2.07066

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -7.98033
THAP11 THAP domain containing 11 -6.29297
SNX6 sorting nexin 6 -3.6137
UBE2C ubiquitin-conjugating enzyme E2C -3.59998
CHIC2 cysteine-rich hydrophobic domain 2 -3.4803
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -3.45695
KDM3A lysine (K)-specific demethylase 3A -3.02142
CIRBP cold inducible RNA binding protein -2.87831
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.69408
GOLT1B golgi transport 1B -2.64373
CREG1 cellular repressor of E1A-stimulated genes 1 -2.58155
STMN1 stathmin 1 -2.40764
FASTKD5 FAST kinase domains 5 -2.32413
CDK1 cyclin-dependent kinase 1 -2.3209
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.31705
GLOD4 glyoxalase domain containing 4 -2.3118
HADH hydroxyacyl-CoA dehydrogenase -2.30563
DUSP14 dual specificity phosphatase 14 -2.25756
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.21346
BASP1 brain abundant, membrane attached signal protein 1 -2.162
USP6NL USP6 N-terminal like -2.02242
HIPK3 homeodomain interacting protein kinase 3 -2.00849