CRCGN015_MCF10A.WT.HP_24H:C09 Gene Set
Genes
59 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
7.00588
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.6299
|
|
WIF1
|
WNT inhibitory factor 1
|
3.41795
|
|
HBA1
|
hemoglobin, alpha 1
|
3.32668
|
|
LAGE3
|
L antigen family, member 3
|
3.31361
|
|
HMOX1
|
heme oxygenase 1
|
3.26093
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.17237
|
|
SH3BP5
|
SH3-domain binding protein 5 (BTK-associated)
|
3.09111
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.84415
|
|
NR1H3
|
nuclear receptor subfamily 1, group H, member 3
|
2.66187
|
|
AGR2
|
anterior gradient 2
|
2.55328
|
|
SPAG4
|
sperm associated antigen 4
|
2.54654
|
|
BANK1
|
B-cell scaffold protein with ankyrin repeats 1
|
2.51738
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
2.42491
|
|
EVL
|
Enah/Vasp-like
|
2.36319
|
|
CASD1
|
CAS1 domain containing 1
|
2.27126
|
|
ALOX15B
|
arachidonate 15-lipoxygenase, type B
|
2.23604
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
2.2107
|
|
CHST2
|
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
|
2.19868
|
|
CLDN8
|
claudin 8
|
2.19634
|
|
CNN2
|
calponin 2
|
2.18475
|
|
MREG
|
melanoregulin
|
2.16834
|
|
TRAT1
|
T cell receptor associated transmembrane adaptor 1
|
2.13783
|
|
CCNE1
|
cyclin E1
|
2.10931
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
2.10213
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
2.10164
|
|
GCLC
|
glutamate-cysteine ligase, catalytic subunit
|
2.09139
|
|
SIRT3
|
sirtuin 3
|
2.07734
|
|
TMEM41B
|
transmembrane protein 41B
|
2.0683
|
|
MTA1
|
metastasis associated 1
|
2.04876
|
|
SLC4A4
|
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
|
2.04547
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
2.04217
|
|
SQSTM1
|
sequestosome 1
|
2.03963
|
|
OLFML2B
|
olfactomedin-like 2B
|
2.01899
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC25B
|
cell division cycle 25B
|
-4.23915
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-4.18985
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.91206
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
-3.9042
|
|
CASC3
|
cancer susceptibility candidate 3
|
-3.64125
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.56996
|
|
BID
|
BH3 interacting domain death agonist
|
-3.24278
|
|
KIF14
|
kinesin family member 14
|
-3.24168
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.15412
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.86434
|
|
KIF20A
|
kinesin family member 20A
|
-2.8163
|
|
MSL1
|
male-specific lethal 1 homolog (Drosophila)
|
-2.69632
|
|
MSN
|
moesin
|
-2.57617
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
-2.444
|
|
MS4A6A
|
membrane-spanning 4-domains, subfamily A, member 6A
|
-2.43069
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.34615
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-2.29786
|
|
MED24
|
mediator complex subunit 24
|
-2.29752
|
|
SAMHD1
|
SAM domain and HD domain 1
|
-2.19102
|
|
CFP
|
complement factor properdin
|
-2.18818
|
|
OGDH
|
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
|
-2.15565
|
|
MTA2
|
metastasis associated 1 family, member 2
|
-2.14879
|
|
RIC8B
|
RIC8 guanine nucleotide exchange factor B
|
-2.11604
|
|
WIPF2
|
WAS/WASL interacting protein family, member 2
|
-2.09101
|
|
TRIOBP
|
TRIO and F-actin binding protein
|
-2.03649
|