CRCGN015_MCF10A.WT.HP_24H:C09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 15-delta-prostaglandin-j2 0.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

59 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 7.00588
TXNRD1 thioredoxin reductase 1 3.6299
WIF1 WNT inhibitory factor 1 3.41795
HBA1 hemoglobin, alpha 1 3.32668
LAGE3 L antigen family, member 3 3.31361
HMOX1 heme oxygenase 1 3.26093
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.17237
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.09111
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.84415
NR1H3 nuclear receptor subfamily 1, group H, member 3 2.66187
AGR2 anterior gradient 2 2.55328
SPAG4 sperm associated antigen 4 2.54654
BANK1 B-cell scaffold protein with ankyrin repeats 1 2.51738
FGFR4 fibroblast growth factor receptor 4 2.42491
EVL Enah/Vasp-like 2.36319
CASD1 CAS1 domain containing 1 2.27126
ALOX15B arachidonate 15-lipoxygenase, type B 2.23604
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.2107
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.19868
CLDN8 claudin 8 2.19634
CNN2 calponin 2 2.18475
MREG melanoregulin 2.16834
TRAT1 T cell receptor associated transmembrane adaptor 1 2.13783
CCNE1 cyclin E1 2.10931
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.10213
ACAA1 acetyl-CoA acyltransferase 1 2.10164
GCLC glutamate-cysteine ligase, catalytic subunit 2.09139
SIRT3 sirtuin 3 2.07734
TMEM41B transmembrane protein 41B 2.0683
MTA1 metastasis associated 1 2.04876
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 2.04547
FBXL12 F-box and leucine-rich repeat protein 12 2.04217
SQSTM1 sequestosome 1 2.03963
OLFML2B olfactomedin-like 2B 2.01899

decreased expression

Symbol Name Standardized Value
CDC25B cell division cycle 25B -4.23915
SCYL3 SCY1-like 3 (S. cerevisiae) -4.18985
ACOT9 acyl-CoA thioesterase 9 -3.91206
DYNLT3 dynein, light chain, Tctex-type 3 -3.9042
CASC3 cancer susceptibility candidate 3 -3.64125
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.56996
BID BH3 interacting domain death agonist -3.24278
KIF14 kinesin family member 14 -3.24168
UBE3C ubiquitin protein ligase E3C -3.15412
TXNDC9 thioredoxin domain containing 9 -2.86434
KIF20A kinesin family member 20A -2.8163
MSL1 male-specific lethal 1 homolog (Drosophila) -2.69632
MSN moesin -2.57617
CREG1 cellular repressor of E1A-stimulated genes 1 -2.444
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -2.43069
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.34615
PGAM4 phosphoglycerate mutase family member 4 -2.29786
MED24 mediator complex subunit 24 -2.29752
SAMHD1 SAM domain and HD domain 1 -2.19102
CFP complement factor properdin -2.18818
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -2.15565
MTA2 metastasis associated 1 family, member 2 -2.14879
RIC8B RIC8 guanine nucleotide exchange factor B -2.11604
WIPF2 WAS/WASL interacting protein family, member 2 -2.09101
TRIOBP TRIO and F-actin binding protein -2.03649