CRCGN015_MCF10A.WT.HP_24H:C13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description oxyquinoline 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 3.85023
AGR2 anterior gradient 2 3.5934
PNKP polynucleotide kinase 3'-phosphatase 3.45641
MAMLD1 mastermind-like domain containing 1 2.71076
COMP cartilage oligomeric matrix protein 2.67969
SNX11 sorting nexin 11 2.63662
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.61698
TLCD3A TLC domain containing 3A 2.55168
KDM5A lysine (K)-specific demethylase 5A 2.1667
ACAA1 acetyl-CoA acyltransferase 1 2.10311
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.07861
TM7SF2 transmembrane 7 superfamily member 2 2.05527
APEH acylaminoacyl-peptide hydrolase 2.03769
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 2.03044
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.00029

decreased expression

Symbol Name Standardized Value
UBE3C ubiquitin protein ligase E3C -4.02431
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.01449
C2CD5 C2 calcium-dependent domain containing 5 -3.99502
GTPBP8 GTP-binding protein 8 (putative) -3.52997
MSN moesin -3.42851
CCNB1 cyclin B1 -3.41562
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.16238
YME1L1 YME1-like 1 ATPase -2.95915
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.95888
KIF20A kinesin family member 20A -2.88119
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.68859
RPA3 replication protein A3, 14kDa -2.55229
NDRG3 NDRG family member 3 -2.18063
MTPAP mitochondrial poly(A) polymerase -2.17558
SLC35B1 solute carrier family 35, member B1 -2.16371
BASP1 brain abundant, membrane attached signal protein 1 -2.06701
TRAPPC3 trafficking protein particle complex 3 -2.05266