CRCGN015_MCF10A.WT.HP_24H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 3.68837
TLR4 toll-like receptor 4 3.43685
WIF1 WNT inhibitory factor 1 3.18451
MCUR1 mitochondrial calcium uniporter regulator 1 2.9312
TBX2 T-box 2 2.58883
COMP cartilage oligomeric matrix protein 2.48152
TXNL4B thioredoxin-like 4B 2.37146
AURKB aurora kinase B 2.22989
NUCB2 nucleobindin 2 2.15182
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.14978
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.13659
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.04778
CERK ceramide kinase 2.04008
GARRE1 granule associated Rac and RHOG effector 1 2.01019

decreased expression

Symbol Name Standardized Value
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -4.70986
VAT1 vesicle amine transport 1 -3.42689
DCK deoxycytidine kinase -3.18955
HMG20B high mobility group 20B -3.17761
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -2.68107
MSN moesin -2.61982
TCTA T-cell leukemia translocation altered -2.20954
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.03753