CRCGN015_MCF10A.WT.HP_24H:C18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TBX2 T-box 2 6.1382
SNAP25 synaptosomal-associated protein, 25kDa 4.40791
FKBP14 FK506 binding protein 14, 22 kDa 2.86198
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.73074
SMIM40 small integral membrane protein 40 2.61069
STMN2 stathmin 2 2.55665
NEFM neurofilament, medium polypeptide 2.50246
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.49223
KDM5A lysine (K)-specific demethylase 5A 2.40025
CKMT1A creatine kinase, mitochondrial 1A 2.39815
PRR15L proline rich 15-like 2.37519
AGR2 anterior gradient 2 2.21999
LAGE3 L antigen family, member 3 2.12804
TEAD3 TEA domain family member 3 2.09943
ADGRE5 adhesion G protein-coupled receptor E5 2.02043
PDLIM1 PDZ and LIM domain 1 2.00651

decreased expression

Symbol Name Standardized Value
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.93869
KIF14 kinesin family member 14 -3.13664
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.04294
MSN moesin -2.95813
TOMM70 translocase of outer mitochondrial membrane 70 -2.84886
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.80862
CD81 CD81 molecule -2.748
RAI14 retinoic acid induced 14 -2.59392
HSPA8 heat shock 70kDa protein 8 -2.34763
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.01439