CRCGN015_MCF10A.WT.HP_24H:D02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description serotonin 33.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.16293
COMP cartilage oligomeric matrix protein 3.43139
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.19953
UBQLN2 ubiquilin 2 3.12459
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.89473
IGHMBP2 immunoglobulin mu binding protein 2 2.75675
ZW10 zw10 kinetochore protein 2.58696
FOS FBJ murine osteosarcoma viral oncogene homolog 2.55968
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.52623
UCMA upper zone of growth plate and cartilage matrix associated 2.30139
CGRRF1 cell growth regulator with ring finger domain 1 2.15699
MRPL11 mitochondrial ribosomal protein L11 2.11647
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.0831
ACVR2B activin A receptor, type IIB 2.08266
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) 2.05617
COL11A1 collagen, type XI, alpha 1 2.04862
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.02612
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 2.01859

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.84398
CD81 CD81 molecule -4.6098
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.45135
FASTKD5 FAST kinase domains 5 -4.11632
RNF167 ring finger protein 167 -3.38186
NPDC1 neural proliferation, differentiation and control, 1 -3.25975
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.94054
ZDHHC6 zinc finger, DHHC-type containing 6 -2.93951
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.84181
GDF15 growth differentiation factor 15 -2.78593
MSN moesin -2.78137
RBM34 RNA binding motif protein 34 -2.71713
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.67985
TRIM9 tripartite motif containing 9 -2.57961
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.41757
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.28187
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.20938
MSMO1 methylsterol monooxygenase 1 -2.13467
USP6NL USP6 N-terminal like -2.11759
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.03671
CXCL5 chemokine (C-X-C motif) ligand 5 -2.02126
TRAF5 TNF receptor-associated factor 5 -2.00614