CRCGN015_MCF10A.WT.HP_24H:D03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description serotonin 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.4395
COMP cartilage oligomeric matrix protein 3.35677
KDM5A lysine (K)-specific demethylase 5A 3.16803
C2CD2 C2 calcium-dependent domain containing 2 2.80578
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.71958
KLHL21 kelch-like family member 21 2.67662
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.62952
TSPAN6 tetraspanin 6 2.29906
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.28589
CADM1 cell adhesion molecule 1 2.25914
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2.20396
RIC8A RIC8 guanine nucleotide exchange factor A 2.14408
SIRT3 sirtuin 3 2.09654
WIF1 WNT inhibitory factor 1 2.03723
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.00345

decreased expression

Symbol Name Standardized Value
DSG2 desmoglein 2 -4.01142
DIPK1A divergent protein kinase domain 1A -3.75309
YME1L1 YME1-like 1 ATPase -3.52546
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.40859
MSMO1 methylsterol monooxygenase 1 -2.97799
CTNND1 catenin (cadherin-associated protein), delta 1 -2.93548
BASP1 brain abundant, membrane attached signal protein 1 -2.79331
TSPAN3 tetraspanin 3 -2.43429
MTPAP mitochondrial poly(A) polymerase -2.09904
THAP11 THAP domain containing 11 -2.07686
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -2.06453