CRCGN015_MCF10A.WT.HP_24H:D06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description fm550 perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 3.7951
CHMP6 charged multivesicular body protein 6 3.76035
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.458
BZW2 basic leucine zipper and W2 domains 2 3.31418
ACAA1 acetyl-CoA acyltransferase 1 2.43526
LGI1 leucine-rich, glioma inactivated 1 2.34099
NEFM neurofilament, medium polypeptide 2.31196
NSG2 neuronal vesicle trafficking associated 2 2.30709
COMP cartilage oligomeric matrix protein 2.24156
STMN2 stathmin 2 2.19479
CADM1 cell adhesion molecule 1 2.19447
SCG3 secretogranin III 2.19094
RGS7 regulator of G-protein signaling 7 2.16562
HAT1 histone acetyltransferase 1 2.09605
TBC1D10C TBC1 domain family, member 10C 2.0662
RAG1 recombination activating gene 1 2.03847
TTYH1 tweety family member 1 2.03218
SNAP91 synaptosomal-associated protein, 91kDa 2.01504
SMIM40 small integral membrane protein 40 2.00768

decreased expression

Symbol Name Standardized Value
TEX10 testis expressed 10 -4.11561
HMG20B high mobility group 20B -3.6482
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.41725
PRPF4 pre-mRNA processing factor 4 -3.14051
JMJD6 jumonji domain containing 6 -2.99406
ARID4B AT rich interactive domain 4B (RBP1-like) -2.84249
LAP3 leucine aminopeptidase 3 -2.8284
MSN moesin -2.81542
HOXA5 homeobox A5 -2.66488
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.55042
CREG1 cellular repressor of E1A-stimulated genes 1 -2.5069
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.42071
MTERF3 mitochondrial transcription termination factor 3 -2.40362
ADGRE5 adhesion G protein-coupled receptor E5 -2.30986
NRIP1 nuclear receptor interacting protein 1 -2.18489