CRCGN015_MCF10A.WT.HP_24H:D09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4-dinitrotoluene 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

61 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.9255
PEX11A peroxisomal biogenesis factor 11 alpha 4.84964
PPARG peroxisome proliferator-activated receptor gamma 4.34417
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.02204
STK10 serine/threonine kinase 10 3.43912
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.96133
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 2.68316
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 2.51135
TLR3 toll-like receptor 3 2.44522
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 2.442
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.44163
MAGEA6 melanoma antigen family A6 2.35593
HMG20A high mobility group 20A 2.35255
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.33229
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 2.27175
TMEM177 transmembrane protein 177 2.25844
ERI2 ERI1 exoribonuclease family member 2 2.23611
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 2.22752
TNS3 tensin 3 2.17514
KRT13 keratin 13, type I 2.15953
RIDA reactive intermediate imine deaminase A homolog 2.14537
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.1235
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.11837
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.1138
HILPDA hypoxia inducible lipid droplet-associated 2.09652
CCDC198 coiled-coil domain containing 198 2.08999
INHBE inhibin, beta E 2.08427
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.08384
RAB21 RAB21, member RAS oncogene family 2.06394
NPC1L1 NPC1-like 1 2.03661
VPS33B vacuolar protein sorting 33 homolog B (yeast) 2.02452
CDHR2 cadherin-related family member 2 2.01178
PBLD phenazine biosynthesis-like protein domain containing 2.00618
CSAG2 CSAG family, member 2 2.00578
MRPL46 mitochondrial ribosomal protein L46 2.00149

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -4.86367
PCCB propionyl CoA carboxylase, beta polypeptide -4.71245
CD44 CD44 molecule (Indian blood group) -4.33711
TRAPPC3 trafficking protein particle complex 3 -4.02725
VDAC1 voltage-dependent anion channel 1 -3.43998
CRTAP cartilage associated protein -3.06741
MSMO1 methylsterol monooxygenase 1 -2.88923
ANXA2 annexin A2 -2.88299
IFRD2 interferon-related developmental regulator 2 -2.63189
TCTA T-cell leukemia translocation altered -2.58583
TKT transketolase -2.47323
TMEM43 transmembrane protein 43 -2.36274
MSN moesin -2.35591
PTDSS2 phosphatidylserine synthase 2 -2.28011
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.26796
KRCC1 lysine-rich coiled-coil 1 -2.2347
BSPRY B-box and SPRY domain containing -2.16512
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.13991
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -2.12571
SCARA3 scavenger receptor class A, member 3 -2.11568
TSC22D4 TSC22 domain family, member 4 -2.11384
CD151 CD151 molecule (Raph blood group) -2.10778
UNC119B unc-119 homolog B (C. elegans) -2.09394
KRT34 keratin 34, type I -2.06517
PLAUR plasminogen activator, urokinase receptor -2.05186
GAS7 growth arrest-specific 7 -2.03913