CRCGN015_MCF10A.WT.HP_24H:D15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,1,1-trichloroethane, technical grade 10.94 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.51693
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.2961
BID BH3 interacting domain death agonist 3.10277
GPER1 G protein-coupled estrogen receptor 1 2.84188
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.82028
ACAA1 acetyl-CoA acyltransferase 1 2.2525
IGHMBP2 immunoglobulin mu binding protein 2 2.02742

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -4.05182
NPDC1 neural proliferation, differentiation and control, 1 -3.9048
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.6681
DSG2 desmoglein 2 -2.91237
ANXA2 annexin A2 -2.29645
CD81 CD81 molecule -2.24623
GDF15 growth differentiation factor 15 -2.23648
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.17635
MSN moesin -2.12363