CRCGN015_MCF10A.WT.HP_24H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-butyl chloride 102.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 3.78703
KCTD5 potassium channel tetramerization domain containing 5 3.4814
CCDC92 coiled-coil domain containing 92 3.30097
KLHL21 kelch-like family member 21 3.30053
OXSR1 oxidative stress responsive 1 3.0963
GATA3 GATA binding protein 3 2.90257
CCL2 chemokine (C-C motif) ligand 2 2.78067
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.37633
SAP30BP SAP30 binding protein 2.30607
TIAM1 T-cell lymphoma invasion and metastasis 1 2.2354
KIZ kizuna centrosomal protein 2.1803
IGFBP6 insulin-like growth factor binding protein 6 2.00607

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -5.7456
SCYL3 SCY1-like 3 (S. cerevisiae) -3.97973
CYCS cytochrome c, somatic -3.5449
NUP93 nucleoporin 93kDa -3.38777
MRPS16 mitochondrial ribosomal protein S16 -3.3625
PUF60 poly-U binding splicing factor 60KDa -3.20957
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.89905
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -2.80967
COG2 component of oligomeric golgi complex 2 -2.75483
FBXO21 F-box protein 21 -2.37572
MSMO1 methylsterol monooxygenase 1 -2.261
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.2587
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.15418
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -2.10587
RPAIN RPA interacting protein -2.09813
SPON1 spondin 1, extracellular matrix protein -2.07993
FGF9 fibroblast growth factor 9 -2.06237
SCRIB scribbled planar cell polarity protein -2.04383
ZNF7 zinc finger protein 7 -2.01537