CRCGN015_MCF10A.WT.HP_24H:D20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumophos 32.42 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.44854
METRN meteorin, glial cell differentiation regulator 4.14923
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.09533
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.15809
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.09591
SESN1 sestrin 1 3.06501
ZDHHC4 zinc finger, DHHC-type containing 4 2.14567
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.04094
RUBCNL rubicon like autophagy enhancer 2.0228

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -5.06512
HMG20B high mobility group 20B -4.97007
MSMO1 methylsterol monooxygenase 1 -4.57569
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.93225
BASP1 brain abundant, membrane attached signal protein 1 -3.10602
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.62523
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.55131
ALDOC aldolase C, fructose-bisphosphate -2.48274
INSIG1 insulin induced gene 1 -2.43865
TCTA T-cell leukemia translocation altered -2.38117
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.20268
HSPA1A heat shock 70kDa protein 1A -2.20004