CRCGN015_MCF10A.WT.HP_24H:D21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description coumophos 10.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 5.16187
COMP cartilage oligomeric matrix protein 5.07918
RAI14 retinoic acid induced 14 3.17959
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.84722
CCL2 chemokine (C-C motif) ligand 2 2.53516
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.40684
MOXD1 monooxygenase, DBH-like 1 2.28975
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 2.28855
GPER1 G protein-coupled estrogen receptor 1 2.20572
LRRC47 leucine rich repeat containing 47 2.09802
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.07676
CCN2 cellular communication network factor 2 2.07107

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -7.84524
REEP5 receptor accessory protein 5 -4.4139
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.19672
MSMO1 methylsterol monooxygenase 1 -3.86623
ARID4B AT rich interactive domain 4B (RBP1-like) -3.72107
CD81 CD81 molecule -3.64402
MSN moesin -2.77839
RALGDS ral guanine nucleotide dissociation stimulator -2.62299
MFSD12 major facilitator superfamily domain containing 12 -2.3586
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.34332
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.34097
INSIG1 insulin induced gene 1 -2.25236