| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n,n-dimethyl-n'-[3-(trifluoromethyl)phenyl]urea 96.55 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COQ8A | coenzyme Q8A | 4.89905 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 3.9569 |
| EPHB2 | EPH receptor B2 | 3.51973 |
| KIF5C | kinesin family member 5C | 3.51924 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.45801 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 3.35312 |
| HBA1 | hemoglobin, alpha 1 | 3.20628 |
| WDR7 | WD repeat domain 7 | 3.12406 |
| COMP | cartilage oligomeric matrix protein | 3.06306 |
| EVL | Enah/Vasp-like | 2.74411 |
| CENPE | centromere protein E, 312kDa | 2.68524 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.62857 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.47306 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.4434 |
| KDM5D | lysine (K)-specific demethylase 5D | 2.40679 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 2.38893 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.36824 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.35046 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 2.31563 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.27274 |
| CADM1 | cell adhesion molecule 1 | 2.26946 |
| RELN | reelin | 2.25895 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.15638 |
| MICU1 | mitochondrial calcium uptake 1 | 2.13869 |
| FBL | fibrillarin | 2.09196 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 2.08777 |
| CLDN3 | claudin 3 | 2.08228 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 2.06115 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 2.05448 |
| KLHDC3 | kelch domain containing 3 | 2.00919 |
| AURKB | aurora kinase B | 2.00766 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AARS1 | alanyl-tRNA synthetase 1 | -4.20739 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.01546 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -3.91077 |
| CCNB1 | cyclin B1 | -3.88706 |
| MSN | moesin | -3.88441 |
| COG2 | component of oligomeric golgi complex 2 | -3.82566 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.74746 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.08573 |
| CD81 | CD81 molecule | -3.01872 |
| GNPAT | glyceronephosphate O-acyltransferase | -2.95028 |
| UBE3C | ubiquitin protein ligase E3C | -2.75914 |
| VDAC1 | voltage-dependent anion channel 1 | -2.75472 |
| RBM34 | RNA binding motif protein 34 | -2.68251 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.59944 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.51901 |
| SMC1A | structural maintenance of chromosomes 1A | -2.41675 |
| SRFBP1 | serum response factor binding protein 1 | -2.34004 |
| TAC4 | tachykinin 4 (hemokinin) | -2.33916 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -2.30645 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.29334 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -2.28669 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.25333 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.22973 |
| ADAR | adenosine deaminase, RNA-specific | -2.22144 |
| TSPAN3 | tetraspanin 3 | -2.18478 |
| CTSL | cathepsin L | -2.1642 |
| LDHB | lactate dehydrogenase B | -2.15657 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.15126 |
| TBCE | tubulin folding cofactor E | -2.11991 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -2.10914 |
| GPC3 | glypican 3 | -2.08848 |
| TUBB6 | tubulin, beta 6 class V | -2.05953 |
| GSDME | gasdermin E | -2.03281 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -2.03133 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.01422 |
| HOMER1 | homer scaffolding protein 1 | -2.0003 |
