CRCGN015_MCF10A.WT.HP_24H:D23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n-dimethyl-n'-[3-(trifluoromethyl)phenyl]urea 32.18 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO10 anoctamin 10 3.27201
COMP cartilage oligomeric matrix protein 2.9961
CCNA1 cyclin A1 2.91112
KLHL21 kelch-like family member 21 2.60106
CGRRF1 cell growth regulator with ring finger domain 1 2.51518
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.30649
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.19681
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.11191

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -4.76333
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.97718
UBE3C ubiquitin protein ligase E3C -3.33495
LYPLA1 lysophospholipase I -2.69663
MSN moesin -2.33372
HMGA2 high mobility group AT-hook 2 -2.1364
OXA1L oxidase (cytochrome c) assembly 1-like -2.10816
SLC35F2 solute carrier family 35, member F2 -2.10118
CD80 CD80 molecule -2.00197