CRCGN015_MCF10A.WT.HP_24H:E04 Gene Set
Genes
47 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.74663
|
|
PRAF2
|
PRA1 domain family, member 2
|
3.57453
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
3.26897
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.99248
|
|
EIF2S3
|
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
|
2.90321
|
|
MDM4
|
MDM4, p53 regulator
|
2.90275
|
|
GATA2
|
GATA binding protein 2
|
2.84775
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.6737
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.64139
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.50055
|
|
TMEM164
|
transmembrane protein 164
|
2.4439
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.42828
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
2.30484
|
|
GPATCH8
|
G patch domain containing 8
|
2.15921
|
|
INCENP
|
inner centromere protein antigens 135/155kDa
|
2.10859
|
|
HNRNPH1
|
heterogeneous nuclear ribonucleoprotein H1 (H)
|
2.06755
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.06603
|
|
CEPT1
|
choline/ethanolamine phosphotransferase 1
|
2.05201
|
|
HNRNPL
|
heterogeneous nuclear ribonucleoprotein L
|
2.03113
|
|
STT3A
|
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
|
2.02442
|
|
SNX11
|
sorting nexin 11
|
2.01509
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DSG2
|
desmoglein 2
|
-3.76493
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.62501
|
|
THAP11
|
THAP domain containing 11
|
-3.28509
|
|
PTK2
|
protein tyrosine kinase 2
|
-3.15945
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.03794
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
-2.80933
|
|
ANXA2
|
annexin A2
|
-2.73177
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-2.73079
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.65084
|
|
HOXA5
|
homeobox A5
|
-2.59988
|
|
DCK
|
deoxycytidine kinase
|
-2.59092
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-2.58315
|
|
FRK
|
fyn-related Src family tyrosine kinase
|
-2.39259
|
|
HTRA1
|
HtrA serine peptidase 1
|
-2.30243
|
|
REEP5
|
receptor accessory protein 5
|
-2.226
|
|
GTF2A2
|
general transcription factor IIA, 2, 12kDa
|
-2.18814
|
|
CDK7
|
cyclin-dependent kinase 7
|
-2.18473
|
|
S100A10
|
S100 calcium binding protein A10
|
-2.16483
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-2.08936
|
|
TM4SF1
|
transmembrane 4 L six family member 1
|
-2.08836
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-2.08054
|
|
DYNC1LI1
|
dynein, cytoplasmic 1, light intermediate chain 1
|
-2.06398
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.03248
|
|
CIAPIN1
|
cytokine induced apoptosis inhibitor 1
|
-2.0233
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.01981
|
|
NUBPL
|
nucleotide binding protein-like
|
-2.01918
|