CRCGN015_MCF10A.WT.HP_24H:E06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description tricresyl phosphate 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ZW10 zw10 kinetochore protein 3.73809
AAMDC adipogenesis associated, Mth938 domain containing 2.97152
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.83924
RPP38 ribonuclease P/MRP 38kDa subunit 2.77934
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.7745
PKN1 protein kinase N1 2.75947
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.73333
EPHB2 EPH receptor B2 2.72162
THAP12 THAP domain containing 12 2.57713
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.54238
KDM5D lysine (K)-specific demethylase 5D 2.40476
RSF1 remodeling and spacing factor 1 2.1856
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.12988
GAB2 GRB2-associated binding protein 2 2.10955

decreased expression

Symbol Name Standardized Value
DIPK1A divergent protein kinase domain 1A -3.82486
SLC35F2 solute carrier family 35, member F2 -3.32407
FASTKD5 FAST kinase domains 5 -3.19908
ZDHHC6 zinc finger, DHHC-type containing 6 -3.10559
DYNLT3 dynein, light chain, Tctex-type 3 -3.06986
TIMP1 TIMP metallopeptidase inhibitor 1 -2.53949
NUSAP1 nucleolar and spindle associated protein 1 -2.47067
MSN moesin -2.42262
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.22246
MTERF3 mitochondrial transcription termination factor 3 -2.17958
GNAS GNAS complex locus -2.11661