CRCGN015_MCF10A.WT.HP_24H:E07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methenamine 100.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.99385
VGLL4 vestigial-like family member 4 3.20342
TBX2 T-box 2 2.55742
ZMIZ1 zinc finger, MIZ-type containing 1 2.50395
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.44905
MMP1 matrix metallopeptidase 1 2.4272

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.45256
PRPF4 pre-mRNA processing factor 4 -4.35723
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.10166
RNF167 ring finger protein 167 -3.85521
CRK v-crk avian sarcoma virus CT10 oncogene homolog -3.51675
PTK2 protein tyrosine kinase 2 -3.36084
VDAC1 voltage-dependent anion channel 1 -3.07606
GDF15 growth differentiation factor 15 -2.22571
CBR1 carbonyl reductase 1 -2.13773
BSPRY B-box and SPRY domain containing -2.08564