CRCGN015_MCF10A.WT.HP_24H:E11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4,4'-methylene-bis(2-methyl?aniline) 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

836 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MSRA methionine sulfoxide reductase A 6.81891
TSKU tsukushi, small leucine rich proteoglycan 5.49957
HLA-DMA major histocompatibility complex, class II, DM alpha 5.17319
KCTD5 potassium channel tetramerization domain containing 5 4.93474
RPL39L ribosomal protein L39-like 4.83095
AMDHD2 amidohydrolase domain containing 2 4.82471
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 4.76224
PYCR1 pyrroline-5-carboxylate reductase 1 4.74195
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.56266
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 4.47258
MKNK1 MAP kinase interacting serine/threonine kinase 1 4.40615
TOM1 target of myb1 (chicken) 4.32918
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 4.24608
AKT1 v-akt murine thymoma viral oncogene homolog 1 4.16273
MECR mitochondrial trans-2-enoyl-CoA reductase 4.14355
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 4.12641
TLCD3A TLC domain containing 3A 4.12289
HMG20B high mobility group 20B 4.12044
CNPY3 canopy FGF signaling regulator 3 4.09031
SRC SRC proto-oncogene, non-receptor tyrosine kinase 4.08838
CASC3 cancer susceptibility candidate 3 4.00896
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.99044
DUSP14 dual specificity phosphatase 14 3.94144
WIF1 WNT inhibitory factor 1 3.92194
SYNGAP1 synaptic Ras GTPase activating protein 1 3.91321
ABHD4 abhydrolase domain containing 4 3.89579
MCOLN1 mucolipin 1 3.8346
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.79648
USP18 ubiquitin specific peptidase 18 3.75238
CAPNS1 calpain, small subunit 1 3.68187
SYNGR3 synaptogyrin 3 3.66946
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 3.66163
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 3.65855
PPIC peptidylprolyl isomerase C (cyclophilin C) 3.65094
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.60598
DHPS deoxyhypusine synthase 3.51037
PLA2G15 phospholipase A2, group XV 3.47746
COPS7A COP9 signalosome subunit 7A 3.47554
NT5DC2 5'-nucleotidase domain containing 2 3.46796
GIPC1 GIPC PDZ domain containing family, member 1 3.44743
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.44065
PMF1-BGLAP PMF1-BGLAP readthrough 3.4147
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 3.38286
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 3.37221
ZNF282 zinc finger protein 282 3.33567
IL2RB interleukin 2 receptor, beta 3.33237
C1QA complement component 1, q subcomponent, A chain 3.32963
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 3.31827
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 3.3131
ABHD6 abhydrolase domain containing 6 3.29314
PNKP polynucleotide kinase 3'-phosphatase 3.29234
PDLIM1 PDZ and LIM domain 1 3.29017
RHOH ras homolog family member H 3.28693
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 3.28188
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 3.2803
TRAPPC3 trafficking protein particle complex 3 3.27479
CYFIP1 cytoplasmic FMR1 interacting protein 1 3.27452
C1QB complement component 1, q subcomponent, B chain 3.26703
SPAG7 sperm associated antigen 7 3.25394
ZNF146 zinc finger protein 146 3.25005
VWA1 von Willebrand factor A domain containing 1 3.23902
GCLC glutamate-cysteine ligase, catalytic subunit 3.23426
STRADA STE20-related kinase adaptor alpha 3.20851
MED24 mediator complex subunit 24 3.18526
EEF2 eukaryotic translation elongation factor 2 3.18347
ALOX5AP arachidonate 5-lipoxygenase-activating protein 3.16857
GET3 guided entry of tail-anchored proteins factor 3, ATPase 3.14883
NIPSNAP1 nipsnap homolog 1 (C. elegans) 3.14091
CMTR1 cap methyltransferase 1 3.13479
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 3.12745
MPDU1 mannose-P-dolichol utilization defect 1 3.10814
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 3.09766
KLHL22 kelch-like family member 22 3.09723
PRR5 proline rich 5 (renal) 3.08187
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 3.0812
FASTK Fas-activated serine/threonine kinase 3.07358
GALE UDP-galactose-4-epimerase 3.06319
NUCB1 nucleobindin 1 3.06099
TBX2 T-box 2 3.03918
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 3.03432
ARFIP2 ADP-ribosylation factor interacting protein 2 3.02963
DNM1 dynamin 1 3.02924
CST7 cystatin F (leukocystatin) 3.02785
GSTA4 glutathione S-transferase alpha 4 3.01312
MAP2K2 mitogen-activated protein kinase kinase 2 3.00832
ARF5 ADP-ribosylation factor 5 2.99312
BHLHE40 basic helix-loop-helix family, member e40 2.98906
PLTP phospholipid transfer protein 2.98729
CXCR4 chemokine (C-X-C motif) receptor 4 2.9817
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.97993
LTF lactotransferrin 2.97446
CLTC clathrin, heavy chain (Hc) 2.96944
SMG9 SMG9 nonsense mediated mRNA decay factor 2.96773
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.96562
U2AF2 U2 small nuclear RNA auxiliary factor 2 2.96421
MRPS2 mitochondrial ribosomal protein S2 2.95924
TCTA T-cell leukemia translocation altered 2.95372
CDK19 cyclin-dependent kinase 19 2.95145
TRIM16 tripartite motif containing 16 2.94194
CD69 CD69 molecule 2.9189
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.90269
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.90181
UBE2S ubiquitin-conjugating enzyme E2S 2.87587
UBE3C ubiquitin protein ligase E3C 2.86592
MRPL12 mitochondrial ribosomal protein L12 2.86523
TMEM187 transmembrane protein 187 2.86502
TRAP1 TNF receptor-associated protein 1 2.85967
NBAS neuroblastoma amplified sequence 2.85661
BTBD2 BTB (POZ) domain containing 2 2.84856
ADAM15 ADAM metallopeptidase domain 15 2.84716
VCY1B variable charge, Y-linked 1B 2.84223
SNAP25 synaptosomal-associated protein, 25kDa 2.84131
AAAS achalasia, adrenocortical insufficiency, alacrimia 2.83849
DNM2 dynamin 2 2.83766
PRMT1 protein arginine methyltransferase 1 2.82724
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 2.82283
TRAF1 TNF receptor-associated factor 1 2.8059
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.80398
ATG7 autophagy related 7 2.79277
SYMPK symplekin 2.79086
PTMS parathymosin 2.7857
MCUR1 mitochondrial calcium uniporter regulator 1 2.78512
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.77709
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.7753
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 2.77126
LAG3 lymphocyte-activation gene 3 2.76901
NUP88 nucleoporin 88kDa 2.76407
AQP4 aquaporin 4 2.74147
CBR1 carbonyl reductase 1 2.74059
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.73423
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.72856
CHPF chondroitin polymerizing factor 2.72617
KLHL26 kelch-like family member 26 2.72495
COL4A2 collagen, type IV, alpha 2 2.718
PTGES2 prostaglandin E synthase 2 2.71711
AGR2 anterior gradient 2 2.7117
PTCD1 pentatricopeptide repeat domain 1 2.71055
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.71022
MOSPD3 motile sperm domain containing 3 2.71
TRIP6 thyroid hormone receptor interactor 6 2.70884
TWF2 twinfilin actin binding protein 2 2.70705
TRIM37 tripartite motif containing 37 2.69916
YJU2B YJU2 splicing factor homolog B 2.68789
MTA1 metastasis associated 1 2.67696
NOP53 NOP53 ribosome biogenesis factor 2.67621
RBM42 RNA binding motif protein 42 2.67119
COG2 component of oligomeric golgi complex 2 2.66884
S100B S100 calcium binding protein B 2.66877
EVL Enah/Vasp-like 2.65989
TLK2 tousled-like kinase 2 2.65981
ENO2 enolase 2 (gamma, neuronal) 2.65802
MED15 mediator complex subunit 15 2.65565
RAB4B RAB4B, member RAS oncogene family 2.65492
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 2.65186
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.651
COMT catechol-O-methyltransferase 2.64869
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 2.63501
DGCR6L DiGeorge syndrome critical region gene 6-like 2.63238
THTPA thiamine triphosphatase 2.62816
CENPB centromere protein B, 80kDa 2.62798
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.62292
DAPK3 death-associated protein kinase 3 2.61434
LRP10 low density lipoprotein receptor-related protein 10 2.60204
HEATR6 HEAT repeat containing 6 2.60082
TUBB4A tubulin, beta 4A class IVa 2.60054
TRIM25 tripartite motif containing 25 2.59975
ACIN1 apoptotic chromatin condensation inducer 1 2.59917
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 2.59875
CADM4 cell adhesion molecule 4 2.59827
MAPK6 mitogen-activated protein kinase 6 2.59193
UNC13D unc-13 homolog D (C. elegans) 2.59141
MVD mevalonate (diphospho) decarboxylase 2.59096
ZNF428 zinc finger protein 428 2.58884
AP1B1 adaptor-related protein complex 1, beta 1 subunit 2.58641
CD151 CD151 molecule (Raph blood group) 2.58378
CD2 CD2 molecule 2.58361
BRIX1 BRX1, biogenesis of ribosomes 2.58164
STX4 syntaxin 4 2.57877
COG4 component of oligomeric golgi complex 4 2.5703
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.56886
MBTPS1 membrane-bound transcription factor peptidase, site 1 2.56803
EML3 echinoderm microtubule associated protein like 3 2.56782
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2.56737
SCARB1 scavenger receptor class B, member 1 2.56587
EPHB3 EPH receptor B3 2.5648
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.56016
TBC1D17 TBC1 domain family, member 17 2.55539
ELOVL5 ELOVL fatty acid elongase 5 2.54911
PHKB phosphorylase kinase, beta 2.54789
TBX19 T-box 19 2.54141
AKT2 v-akt murine thymoma viral oncogene homolog 2 2.53176
NLRP2B NLR family pyrin domain containing 2B 2.53098
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 2.52619
NAPSA napsin A aspartic peptidase 2.52556
CDK6 cyclin-dependent kinase 6 2.52386
PLS1 plastin 1 2.51311
BIN2 bridging integrator 2 2.51283
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.51041
MAP3K6 mitogen-activated protein kinase kinase kinase 6 2.50058
PRPF31 pre-mRNA processing factor 31 2.49645
MCM3 minichromosome maintenance complex component 3 2.49621
PRKCD protein kinase C, delta 2.49451
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.49346
TTC38 tetratricopeptide repeat domain 38 2.48951
SFTPB surfactant protein B 2.48582
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.48466
LGALS8 lectin, galactoside-binding, soluble, 8 2.48296
MAN2B1 mannosidase, alpha, class 2B, member 1 2.48127
VSIG4 V-set and immunoglobulin domain containing 4 2.48078
FAM193B family with sequence similarity 193, member B 2.47966
KIFAP3 kinesin-associated protein 3 2.472
NNT nicotinamide nucleotide transhydrogenase 2.47062
MRGBP MRG/MORF4L binding protein 2.47053
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.46804
DRC9 dynein regulatory complex subunit 9 2.4662
KAT5 K(lysine) acetyltransferase 5 2.46362
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 2.46128
FLOT1 flotillin 1 2.45947
RING1 ring finger protein 1 2.45753
PGAM4 phosphoglycerate mutase family member 4 2.45732
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.44996
ANO10 anoctamin 10 2.42877
MREG melanoregulin 2.42719
SECISBP2L SECIS binding protein 2-like 2.42632
CXCL13 chemokine (C-X-C motif) ligand 13 2.42488
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 2.41314
UBE2M ubiquitin-conjugating enzyme E2M 2.41008
ALG6 ALG6, alpha-1,3-glucosyltransferase 2.40645
ZNF862 zinc finger protein 862 2.39915
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.39592
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.38789
UCK2 uridine-cytidine kinase 2 2.38619
CYB561 cytochrome b561 2.3858
RPRD2 regulation of nuclear pre-mRNA domain containing 2 2.38525
TSC22D4 TSC22 domain family, member 4 2.38473
MYO18A myosin XVIIIA 2.38353
ITPKC inositol-trisphosphate 3-kinase C 2.37775
MSX1 msh homeobox 1 2.37286
ZNF518A zinc finger protein 518A 2.36885
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 2.36652
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.36614
KXD1 KxDL motif containing 1 2.36539
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 2.36425
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 2.36189
EMID1 EMI domain containing 1 2.35991
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.3598
P4HB prolyl 4-hydroxylase, beta polypeptide 2.35752
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.35728
SRRM5 serine/arginine repetitive matrix 5 2.35676
CLCN3 chloride channel, voltage-sensitive 3 2.35586
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.3549
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 2.35477
NUP133 nucleoporin 133kDa 2.3506
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 2.34788
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.34567
TMEM147 transmembrane protein 147 2.34547
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 2.3417
MLF2 myeloid leukemia factor 2 2.33986
RHOA ras homolog family member A 2.33636
PRAME preferentially expressed antigen in melanoma 2.33359
MAN1B1 mannosidase, alpha, class 1B, member 1 2.32811
TLE5 TLE family member 5, transcriptional modulator 2.31814
SPTBN4 spectrin, beta, non-erythrocytic 4 2.31238
KCTD7 potassium channel tetramerization domain containing 7 2.3038
PGC progastricsin (pepsinogen C) 2.30202
HPR haptoglobin-related protein 2.29626
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.28861
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 2.28755
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.28597
BCL7B B-cell CLL/lymphoma 7B 2.28534
HPGDS hematopoietic prostaglandin D synthase 2.28464
PTPRJ protein tyrosine phosphatase, receptor type, J 2.28452
HOPX HOP homeobox 2.28176
KLHDC3 kelch domain containing 3 2.28057
YIPF2 Yip1 domain family, member 2 2.27936
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 2.2787
CNTLN centlein, centrosomal protein 2.27834
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.27465
THAP7 THAP domain containing 7 2.27277
GMPPA GDP-mannose pyrophosphorylase A 2.26537
DENND2D DENN/MADD domain containing 2D 2.26498
STX10 syntaxin 10 2.26286
SSNA1 Sjogren syndrome nuclear autoantigen 1 2.25864
RXRA retinoid X receptor, alpha 2.25829
SIDT1 SID1 transmembrane family, member 1 2.2582
NAGA N-acetylgalactosaminidase, alpha- 2.25701
RSU1 Ras suppressor protein 1 2.25674
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 2.25499
POLR1A polymerase (RNA) I polypeptide A, 194kDa 2.25343
REXO2 RNA exonuclease 2 2.2515
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.25092
FAM3C family with sequence similarity 3, member C 2.2466
MELTF melanotransferrin 2.24639
VTA1 vesicle (multivesicular body) trafficking 1 2.24064
NXT2 nuclear transport factor 2-like export factor 2 2.2399
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 2.23383
PCDHB16 protocadherin beta 16 2.23328
DMAC2 distal membrane arm assembly component 2 2.22948
MRM3 mitochondrial rRNA methyltransferase 3 2.2278
PRUNE1 prune exopolyphosphatase 1 2.22495
MEOX2 mesenchyme homeobox 2 2.22307
ATP9B ATPase, class II, type 9B 2.22293
TUBD1 tubulin, delta 1 2.2221
GALK1 galactokinase 1 2.21637
DENND2B DENN domain containing 2B 2.21633
MEX3D mex-3 RNA binding family member D 2.21291
ZBTB32 zinc finger and BTB domain containing 32 2.21132
WBP2 WW domain binding protein 2 2.2113
CLDN4 claudin 4 2.20955
GAS2L1 growth arrest-specific 2 like 1 2.20762
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.20342
GRWD1 glutamate-rich WD repeat containing 1 2.20322
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 2.20127
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.19776
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.19608
PCNA proliferating cell nuclear antigen 2.19243
ZDHHC18 zinc finger, DHHC-type containing 18 2.19152
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.19054
SLC39A1 solute carrier family 39 (zinc transporter), member 1 2.1838
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.18299
POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3 2.17847
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.17831
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.17824
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.17567
UBL3 ubiquitin-like 3 2.17331
BOLA1 bolA family member 1 2.17327
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 2.17281
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.17122
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.17024
EFNA3 ephrin-A3 2.16976
RAB35 RAB35, member RAS oncogene family 2.16969
B3GAT3 beta-1,3-glucuronyltransferase 3 2.16479
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 2.16256
KRT1 keratin 1, type II 2.15998
MAST2 microtubule associated serine/threonine kinase 2 2.15997
KYAT1 kynurenine aminotransferase 1 2.15984
ZBTB24 zinc finger and BTB domain containing 24 2.15952
TMEM259 transmembrane protein 259 2.15915
CFHR3 complement factor H-related 3 2.15832
PARVB parvin, beta 2.15814
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.15533
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 2.15527
BLVRB biliverdin reductase B 2.15346
MAPKAP1 mitogen-activated protein kinase associated protein 1 2.15176
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 2.15144
GPS1 G protein pathway suppressor 1 2.15054
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 2.15025
ARL5A ADP-ribosylation factor-like 5A 2.14909
BCAS4 breast carcinoma amplified sequence 4 2.14857
ARMC6 armadillo repeat containing 6 2.14787
HLA-DMB major histocompatibility complex, class II, DM beta 2.147
NT5C 5', 3'-nucleotidase, cytosolic 2.14678
PMM1 phosphomannomutase 1 2.14522
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 2.14519
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.14045
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.13842
PCBP4 poly(rC) binding protein 4 2.13798
ALX1 ALX homeobox 1 2.13706
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.13658
MIA melanoma inhibitory activity 2.13447
AARS1 alanyl-tRNA synthetase 1 2.13402
ASIC1 acid sensing (proton gated) ion channel 1 2.13122
SPOUT1 SPOUT domain containing methyltransferase 1 2.13118
DNAL4 dynein, axonemal, light chain 4 2.13113
LYPD3 LY6/PLAUR domain containing 3 2.13097
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 2.13049
OXA1L oxidase (cytochrome c) assembly 1-like 2.12994
CPAP centrosome assembly and centriole elongation protein 2.12978
SDHAF1 succinate dehydrogenase complex assembly factor 1 2.12846
COL4A1 collagen, type IV, alpha 1 2.12722
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.12619
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.12322
ACTN4 actinin, alpha 4 2.12218
ADGRL1 adhesion G protein-coupled receptor L1 2.12158
ELAVL1 ELAV like RNA binding protein 1 2.11781
RHOB ras homolog family member B 2.11555
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 2.11294
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.11231
ISOC2 isochorismatase domain containing 2 2.10984
CCDC86 coiled-coil domain containing 86 2.10855
PMVK phosphomevalonate kinase 2.10807
SF3B4 splicing factor 3b, subunit 4, 49kDa 2.10397
CHI3L2 chitinase 3-like 2 2.1034
SYT2 synaptotagmin II 2.10213
TMEM161A transmembrane protein 161A 2.10168
ZDHHC24 zinc finger, DHHC-type containing 24 2.09823
ECHDC2 enoyl CoA hydratase domain containing 2 2.0981
ETHE1 ethylmalonic encephalopathy 1 2.09766
SNX11 sorting nexin 11 2.09556
ZNF212 zinc finger protein 212 2.09246
KIF5B kinesin family member 5B 2.09122
IL32 interleukin 32 2.09053
PYGL phosphorylase, glycogen, liver 2.08798
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.0854
TMEM168 transmembrane protein 168 2.08348
PSD4 pleckstrin and Sec7 domain containing 4 2.08294
CDC37 cell division cycle 37 2.07908
DTNA dystrobrevin, alpha 2.07906
AP5M1 adaptor-related protein complex 5, mu 1 subunit 2.07697
YJU2 YJU2 splicing factor homolog 2.07632
KRI1 KRI1 homolog (S. cerevisiae) 2.07598
IRF3 interferon regulatory factor 3 2.07098
GSAP gamma-secretase activating protein 2.06968
DIO2 deiodinase, iodothyronine, type II 2.069
ZNF571 zinc finger protein 571 2.06492
KCTD13 potassium channel tetramerization domain containing 13 2.0623
ICAM3 intercellular adhesion molecule 3 2.06058
CUL7 cullin 7 2.04601
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 2.04562
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.04322
FADS2 fatty acid desaturase 2 2.04214
CHERP calcium homeostasis endoplasmic reticulum protein 2.04095
MYT1 myelin transcription factor 1 2.04089
LZTR1 leucine-zipper-like transcription regulator 1 2.03313
INTS12 integrator complex subunit 12 2.03075
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.02956
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.0295
LMO4 LIM domain only 4 2.02948
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 2.02875
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.0272
RTL8C retrotransposon Gag like 8C 2.02511
NABP2 nucleic acid binding protein 2 2.0251
ZIC1 Zic family member 1 2.02372
SCN1B sodium channel, voltage gated, type I beta subunit 2.02334
ABHD17A abhydrolase domain containing 17A 2.02326
CCL4 chemokine (C-C motif) ligand 4 2.02292
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 2.02145
INO80B INO80 complex subunit B 2.02127
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.01312
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.01096
LGALS7B lectin, galactoside-binding, soluble, 7B 2.00749
GPM6A glycoprotein M6A 2.00694
P3H3 prolyl 3-hydroxylase 3 2.00683
ILRUN inflammation and lipid regulator with UBA-like and NBR1-like domains 2.00585
MKS1 Meckel syndrome, type 1 2.00562
RHOC ras homolog family member C 2.00349
CDH18 cadherin 18, type 2 2.0016
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.00133
CYB5A cytochrome b5 type A (microsomal) 2.00005

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.18612
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -6.69391
CDPF1 cysteine-rich, DPF motif domain containing 1 -6.63196
RPN1 ribophorin I -6.47358
SMNDC1 survival motor neuron domain containing 1 -6.0321
NGRN neugrin, neurite outgrowth associated -6.02526
GDF15 growth differentiation factor 15 -5.828
NUP93 nucleoporin 93kDa -5.75631
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -5.25895
MTFR1 mitochondrial fission regulator 1 -4.89028
USP22 ubiquitin specific peptidase 22 -4.81214
MRPL18 mitochondrial ribosomal protein L18 -4.42887
LRRC41 leucine rich repeat containing 41 -4.36828
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -4.2446
PRPF4 pre-mRNA processing factor 4 -4.14157
CAB39 calcium binding protein 39 -4.06897
ADD3 adducin 3 (gamma) -4.06786
CYCS cytochrome c, somatic -4.06101
ELAC2 elaC ribonuclease Z 2 -3.94582
CBR3 carbonyl reductase 3 -3.9286
LBR lamin B receptor -3.88576
SGCE sarcoglycan, epsilon -3.88111
PCNP PEST proteolytic signal containing nuclear protein -3.8704
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -3.86064
TBPL1 TBP-like 1 -3.81709
CRYZ crystallin, zeta (quinone reductase) -3.79644
TM9SF2 transmembrane 9 superfamily member 2 -3.77862
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.76978
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -3.75447
CCNH cyclin H -3.73921
AZIN1 antizyme inhibitor 1 -3.67608
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -3.65024
GOLT1B golgi transport 1B -3.61273
BID BH3 interacting domain death agonist -3.60848
TFDP1 transcription factor Dp-1 -3.56232
PRCP prolylcarboxypeptidase (angiotensinase C) -3.55465
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -3.5495
UFM1 ubiquitin-fold modifier 1 -3.53959
CCP110 centriolar coiled coil protein 110kDa -3.52765
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -3.51573
HAUS2 HAUS augmin-like complex, subunit 2 -3.48275
FBXO21 F-box protein 21 -3.47719
PDE1A phosphodiesterase 1A, calmodulin-dependent -3.46134
PRKX protein kinase, X-linked -3.4595
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -3.45769
SGK1 serum/glucocorticoid regulated kinase 1 -3.45329
TM9SF3 transmembrane 9 superfamily member 3 -3.41338
GLOD4 glyoxalase domain containing 4 -3.38556
PHKG2 phosphorylase kinase, gamma 2 (testis) -3.37537
UBE2C ubiquitin-conjugating enzyme E2C -3.36548
RBM22 RNA binding motif protein 22 -3.32885
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -3.30311
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -3.2958
BAG3 BCL2-associated athanogene 3 -3.28673
TXNDC9 thioredoxin domain containing 9 -3.28562
MSN moesin -3.22761
RAP1GAP2 RAP1 GTPase activating protein 2 -3.18987
HAT1 histone acetyltransferase 1 -3.17588
ISOC1 isochorismatase domain containing 1 -3.16522
ARHGAP29 Rho GTPase activating protein 29 -3.14482
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.1419
THBS2 thrombospondin 2 -3.14083
TGIF2 TGFB-induced factor homeobox 2 -3.13752
MOK MOK protein kinase -3.13654
CXCL12 chemokine (C-X-C motif) ligand 12 -3.13384
CPE carboxypeptidase E -3.11953
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -3.11371
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -3.11251
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -3.10181
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.09921
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.07903
FZD6 frizzled class receptor 6 -3.07885
FNBP1L formin binding protein 1-like -3.07023
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -3.06633
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 -3.05936
TIMP1 TIMP metallopeptidase inhibitor 1 -3.05563
TFPI2 tissue factor pathway inhibitor 2 -3.04913
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.03763
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -3.03693
ZNF250 zinc finger protein 250 -3.032
ZC2HC1A zinc finger, C2HC-type containing 1A -3.03009
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -3.015
PAQR3 progestin and adipoQ receptor family member III -3.01105
MSMO1 methylsterol monooxygenase 1 -2.99276
ZFAND1 zinc finger, AN1-type domain 1 -2.99021
FAM168B family with sequence similarity 168, member B -2.98811
SLC35F2 solute carrier family 35, member F2 -2.97695
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa -2.96657
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.96501
UBQLN2 ubiquilin 2 -2.94834
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.94387
DENND1A DENN/MADD domain containing 1A -2.929
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.90402
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.89572
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -2.88699
EAPP E2F-associated phosphoprotein -2.88469
ENOPH1 enolase-phosphatase 1 -2.84813
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -2.84797
HTRA1 HtrA serine peptidase 1 -2.8422
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.84143
SETD4 SET domain containing 4 -2.83622
SOAT2 sterol O-acyltransferase 2 -2.82534
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.81591
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.8127
HSPH1 heat shock 105kDa/110kDa protein 1 -2.81215
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -2.81184
ATRAID all-trans retinoic acid-induced differentiation factor -2.8089
DSG2 desmoglein 2 -2.80433
ACVR1 activin A receptor, type I -2.80358
JADE3 jade family PHD finger 3 -2.79754
THNSL1 threonine synthase-like 1 (S. cerevisiae) -2.79191
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.79012
TIMCC TIM double twin CX3C motif chaperone -2.77801
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -2.77489
ANXA7 annexin A7 -2.76698
OSBPL11 oxysterol binding protein-like 11 -2.75922
PF4 platelet factor 4 -2.75446
ZNF165 zinc finger protein 165 -2.74944
IFRD2 interferon-related developmental regulator 2 -2.74069
VCAN versican -2.73682
WWP1 WW domain containing E3 ubiquitin protein ligase 1 -2.73035
SARAF store-operated calcium entry-associated regulatory factor -2.72299
FAIM Fas apoptotic inhibitory molecule -2.72228
CUZD1 CUB and zona pellucida-like domains 1 -2.70461
ADI1 acireductone dioxygenase 1 -2.7046
EBAG9 estrogen receptor binding site associated, antigen, 9 -2.70305
BRCA1 breast cancer 1, early onset -2.70168
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.69983
WRN Werner syndrome, RecQ helicase-like -2.69948
MSLN mesothelin -2.69826
PEX11A peroxisomal biogenesis factor 11 alpha -2.6919
THAP11 THAP domain containing 11 -2.69006
TPP2 tripeptidyl peptidase II -2.67771
UBE2W ubiquitin-conjugating enzyme E2W (putative) -2.67598
TRIM45 tripartite motif containing 45 -2.67376
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.66768
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific -2.65672
TNS4 tensin 4 -2.65334
RECK reversion-inducing-cysteine-rich protein with kazal motifs -2.64037
GLIPR1 GLI pathogenesis-related 1 -2.63643
HSF2BP heat shock transcription factor 2 binding protein -2.6359
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H -2.63499
GARS1 glycyl-tRNA synthetase 1 -2.63456
WDR3 WD repeat domain 3 -2.62835
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -2.61634
CCND3 cyclin D3 -2.61424
ZC3H7A zinc finger CCCH-type containing 7A -2.61218
ADGRG6 adhesion G protein-coupled receptor G6 -2.61171
STXBP2 syntaxin binding protein 2 -2.61138
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.60441
ANKRD6 ankyrin repeat domain 6 -2.6011
MAT2A methionine adenosyltransferase II, alpha -2.60002
PCBP1 poly(rC) binding protein 1 -2.59819
TWSG1 twisted gastrulation BMP signaling modulator 1 -2.59177
POLK polymerase (DNA directed) kappa -2.58471
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.5846
MED7 mediator complex subunit 7 -2.58404
ADIRF adipogenesis regulatory factor -2.5816
DENND10 DENN domain containing 10 -2.58138
JRKL JRK-like -2.5762
POGLUT2 protein O-glucosyltransferase 2 -2.57407
MXRA8 matrix-remodelling associated 8 -2.56703
MKNK2 MAP kinase interacting serine/threonine kinase 2 -2.5608
BICC1 BicC family RNA binding protein 1 -2.558
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.55519
CTBP2 C-terminal binding protein 2 -2.55236
BOLA2B bolA family member 2B -2.55182
MACO1 macoilin 1 -2.54281
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -2.54175
NKAPD1 NKAP domain containing 1 -2.53343
RPA3 replication protein A3, 14kDa -2.53058
ABRAXAS2 abraxas 2, BRISC complex subunit -2.53047
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -2.52948
RCOR3 REST corepressor 3 -2.52851
WASHC5 WASH complex subunit 5 -2.52336
RWDD3 RWD domain containing 3 -2.51485
ZNF623 zinc finger protein 623 -2.51397
COQ8A coenzyme Q8A -2.51174
STAU1 staufen double-stranded RNA binding protein 1 -2.50455
TATDN2 TatD DNase domain containing 2 -2.50402
WWC1 WW and C2 domain containing 1 -2.50163
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha -2.49648
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.49331
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 -2.4885
EBNA1BP2 EBNA1 binding protein 2 -2.4884
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -2.48692
GPR20 G protein-coupled receptor 20 -2.48516
WBP1L WW domain binding protein 1-like -2.46632
SLC25A46 solute carrier family 25, member 46 -2.45302
ZNF217 zinc finger protein 217 -2.45208
THBS1 thrombospondin 1 -2.4512
PDGFC platelet derived growth factor C -2.44336
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -2.43713
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.4305
PTK2 protein tyrosine kinase 2 -2.41068
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.40825
FAM13B family with sequence similarity 13, member B -2.40363
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -2.39851
DPEP1 dipeptidase 1 (renal) -2.39536
FKBP14 FK506 binding protein 14, 22 kDa -2.39155
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -2.3862
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 -2.37723
SQOR sulfide quinone oxidoreductase -2.377
ZNF215 zinc finger protein 215 -2.37427
IMPACT impact RWD domain protein -2.37375
RB1 retinoblastoma 1 -2.36959
UROS uroporphyrinogen III synthase -2.36431
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.3613
IGF2 insulin-like growth factor 2 -2.35641
PELI1 pellino E3 ubiquitin protein ligase 1 -2.35387
SEC24B SEC24 family member B -2.35357
LY75-CD302 LY75-CD302 readthrough -2.3511
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.35018
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -2.34758
WDR73 WD repeat domain 73 -2.34741
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.34154
KDM3A lysine (K)-specific demethylase 3A -2.34104
CTRL chymotrypsin-like -2.34032
COL10A1 collagen, type X, alpha 1 -2.34003
COPS8 COP9 signalosome subunit 8 -2.3396
TAOK1 TAO kinase 1 -2.33891
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 -2.3384
YIPF4 Yip1 domain family, member 4 -2.33761
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -2.33121
GRAMD1C GRAM domain containing 1C -2.33113
ELOC elongin C -2.32496
MED4 mediator complex subunit 4 -2.3195
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -2.3127
ALCAM activated leukocyte cell adhesion molecule -2.31068
PDE10A phosphodiesterase 10A -2.30679
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.30663
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -2.30585
CYRIA CYFIP related Rac1 interactor A -2.30475
RAI2 retinoic acid induced 2 -2.3012
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.2972
ANKRD55 ankyrin repeat domain 55 -2.29658
TUBB6 tubulin, beta 6 class V -2.29522
RUVBL1 RuvB-like AAA ATPase 1 -2.29177
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -2.28779
PRKCI protein kinase C, iota -2.28704
PPCS phosphopantothenoylcysteine synthetase -2.28683
SMIM40 small integral membrane protein 40 -2.28359
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 -2.2827
WDR43 WD repeat domain 43 -2.27713
PNMA8A PNMA family member 8A -2.27584
PLSCR1 phospholipid scramblase 1 -2.27466
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -2.26796
WDR26 WD repeat domain 26 -2.25852
CCNB2 cyclin B2 -2.25333
TTC19 tetratricopeptide repeat domain 19 -2.25111
PNPLA4 patatin-like phospholipase domain containing 4 -2.25017
MCMBP minichromosome maintenance complex binding protein -2.24713
ORC6 origin recognition complex, subunit 6 -2.24539
TEX10 testis expressed 10 -2.24342
NCK2 NCK adaptor protein 2 -2.24257
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -2.2417
LCMT2 leucine carboxyl methyltransferase 2 -2.24152
TOB1 transducer of ERBB2, 1 -2.23933
AOX1 aldehyde oxidase 1 -2.23812
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides -2.23772
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -2.23544
FUBP1 far upstream element (FUSE) binding protein 1 -2.23409
ERLIN2 ER lipid raft associated 2 -2.23051
CD40LG CD40 ligand -2.22804
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.22729
RAB21 RAB21, member RAS oncogene family -2.2259
IFNGR1 interferon gamma receptor 1 -2.22477
COASY CoA synthase -2.22222
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.22079
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -2.21926
TOMM34 translocase of outer mitochondrial membrane 34 -2.21902
SDCBP syndecan binding protein (syntenin) -2.21879
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.21866
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.21584
MPO myeloperoxidase -2.21552
FNDC3A fibronectin type III domain containing 3A -2.21463
THBD thrombomodulin -2.21243
CSPP1 centrosome and spindle pole associated protein 1 -2.21012
CCN2 cellular communication network factor 2 -2.20748
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 -2.2064
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -2.20287
MYL9 myosin, light chain 9, regulatory -2.20265
UMOD uromodulin -2.20146
RAP1B RAP1B, member of RAS oncogene family -2.19962
ZBED2 zinc finger, BED-type containing 2 -2.19798
ARID4A AT rich interactive domain 4A (RBP1-like) -2.19739
PHF10 PHD finger protein 10 -2.19614
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) -2.19461
RABGGTB Rab geranylgeranyltransferase, beta subunit -2.19326
STAMBP STAM binding protein -2.19043
ISYNA1 inositol-3-phosphate synthase 1 -2.1895
KLF3 Kruppel-like factor 3 (basic) -2.18946
ZNF706 zinc finger protein 706 -2.18928
KIF2C kinesin family member 2C -2.18602
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -2.18293
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -2.18021
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -2.17943
RPGRIP1L RPGRIP1-like -2.17567
TGDS TDP-glucose 4,6-dehydratase -2.17433
HTN3 histatin 3 -2.17232
HAL histidine ammonia-lyase -2.16154
DDIT4 DNA-damage-inducible transcript 4 -2.15077
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.1502
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.14914
PROSER1 proline and serine rich 1 -2.14847
ZNF611 zinc finger protein 611 -2.14796
ADAM17 ADAM metallopeptidase domain 17 -2.145
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.14355
MSL3 male-specific lethal 3 homolog (Drosophila) -2.14295
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -2.14133
NFU1 NFU1 iron-sulfur cluster scaffold -2.13598
ALPK1 alpha-kinase 1 -2.13514
LARP1 La ribonucleoprotein domain family, member 1 -2.1327
ZNF423 zinc finger protein 423 -2.13255
KDM3B lysine (K)-specific demethylase 3B -2.13195
CELA2A chymotrypsin-like elastase family, member 2A -2.1282
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -2.12802
ANXA1 annexin A1 -2.12289
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.12027
STARD7 StAR-related lipid transfer (START) domain containing 7 -2.11718
BBIP1 BBSome interacting protein 1 -2.11702
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -2.11679
MCFD2 multiple coagulation factor deficiency 2 -2.11643
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.11641
MMD monocyte to macrophage differentiation-associated -2.11608
GULP1 GULP, engulfment adaptor PTB domain containing 1 -2.11515
PSMC3IP PSMC3 interacting protein -2.11474
FAM114A2 family with sequence similarity 114, member A2 -2.11313
COX6C cytochrome c oxidase subunit VIc -2.11259
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -2.11008
PDE2A phosphodiesterase 2A, cGMP-stimulated -2.10779
NANS N-acetylneuraminic acid synthase -2.10719
CASP6 caspase 6, apoptosis-related cysteine peptidase -2.10375
FANCF Fanconi anemia, complementation group F -2.10319
PEX3 peroxisomal biogenesis factor 3 -2.10263
VPS33B vacuolar protein sorting 33 homolog B (yeast) -2.09991
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase -2.09964
ZNF7 zinc finger protein 7 -2.0974
ELOVL6 ELOVL fatty acid elongase 6 -2.09406
NUDC nudC nuclear distribution protein -2.09298
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.09278
KIRREL1 kirre like nephrin family adhesion molecule 1 -2.08943
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) -2.08724
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.08665
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.08558
ADGRL4 adhesion G protein-coupled receptor L4 -2.08518
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -2.08154
OGN osteoglycin -2.07571
MBNL1 muscleblind-like splicing regulator 1 -2.07555
FGD6 FYVE, RhoGEF and PH domain containing 6 -2.07381
HCCS holocytochrome c synthase -2.07339
HNRNPK heterogeneous nuclear ribonucleoprotein K -2.06843
NT5E 5'-nucleotidase, ecto (CD73) -2.06729
BPHL biphenyl hydrolase-like (serine hydrolase) -2.06715
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -2.06709
MRS2 MRS2 magnesium transporter -2.06596
PNLIP pancreatic lipase -2.06338
MPC1 mitochondrial pyruvate carrier 1 -2.05636
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -2.05599
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.05568
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough -2.05511
EI24 etoposide induced 2.4 -2.0549
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.05387
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.05371
KPNA5 karyopherin alpha 5 (importin alpha 6) -2.05268
HIKESHI heat shock protein nuclear import factor hikeshi -2.05006
AIG1 androgen-induced 1 -2.04788
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.04563
ZNF721 zinc finger protein 721 -2.04473
CUL4A cullin 4A -2.04205
PDIA3 protein disulfide isomerase family A, member 3 -2.04137
PKP2 plakophilin 2 -2.04044
BMP6 bone morphogenetic protein 6 -2.03829
ZMYM4 zinc finger, MYM-type 4 -2.03746
MTERF3 mitochondrial transcription termination factor 3 -2.03383
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -2.03276
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -2.03272
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -2.03267
GOLT1A golgi transport 1A -2.03205
MBOAT2 membrane bound O-acyltransferase domain containing 2 -2.0285
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.02816
HACD2 3-hydroxyacyl-CoA dehydratase 2 -2.0272
PHOX2B paired-like homeobox 2b -2.02614
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.02204
ATG2B autophagy related 2B -2.02028
FAM171A1 family with sequence similarity 171, member A1 -2.01972
NUP107 nucleoporin 107kDa -2.01588
BTG3 BTG family, member 3 -2.01519
HEMK2 HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine -2.01405
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.01168
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.01146
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -2.01094
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -2.00897
TCP1 t-complex 1 -2.00732
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.00561
PDE8A phosphodiesterase 8A -2.0026
PRR13 proline rich 13 -2.00107