CRCGN015_MCF10A.WT.HP_24H:E12 Gene Set
Genes
39 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
6.8366
|
|
TLR4
|
toll-like receptor 4
|
3.64768
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.45754
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.31881
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.2143
|
|
GLOD4
|
glyoxalase domain containing 4
|
2.99676
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
2.87595
|
|
GSPT2
|
G1 to S phase transition 2
|
2.70202
|
|
HBA1
|
hemoglobin, alpha 1
|
2.49674
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
2.46256
|
|
CCNF
|
cyclin F
|
2.43197
|
|
TSPAN8
|
tetraspanin 8
|
2.27473
|
|
ZNF365
|
zinc finger protein 365
|
2.27164
|
|
NRBF2
|
nuclear receptor binding factor 2
|
2.22072
|
|
DUSP3
|
dual specificity phosphatase 3
|
2.18105
|
|
CCN6
|
cellular communication network factor 6
|
2.12751
|
|
SPAG6
|
sperm associated antigen 6
|
2.12583
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.12094
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.1034
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.05337
|
|
NUDT11
|
nudix (nucleoside diphosphate linked moiety X)-type motif 11
|
2.0259
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KIF14
|
kinesin family member 14
|
-6.60862
|
|
TES
|
testin LIM domain protein
|
-3.51008
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-3.41282
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.97931
|
|
RNF167
|
ring finger protein 167
|
-2.94606
|
|
PTK2
|
protein tyrosine kinase 2
|
-2.80531
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-2.63563
|
|
GDF15
|
growth differentiation factor 15
|
-2.39162
|
|
ATG3
|
autophagy related 3
|
-2.37951
|
|
FASN
|
fatty acid synthase
|
-2.30708
|
|
PFN1
|
profilin 1
|
-2.29862
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-2.23256
|
|
ASPM
|
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
|
-2.20844
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.18872
|
|
PGCKA1
|
PDCD10 and GCKIII kinases associated 1
|
-2.14373
|
|
CAV1
|
caveolin 1, caveolae protein, 22kDa
|
-2.13997
|
|
RGS19
|
regulator of G-protein signaling 19
|
-2.1051
|
|
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
|
-2.02699
|