CRCGN015_MCF10A.WT.HP_24H:E14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bisphenol-a 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

89 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 7.14674
HBA1 hemoglobin, alpha 1 5.17044
SNX11 sorting nexin 11 4.04495
CXCL2 chemokine (C-X-C motif) ligand 2 4.01264
MAP7 microtubule-associated protein 7 3.68325
ANO10 anoctamin 10 3.60845
WIF1 WNT inhibitory factor 1 3.39684
INTS3 integrator complex subunit 3 3.39561
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.31465
STXBP1 syntaxin binding protein 1 3.08921
FGFR4 fibroblast growth factor receptor 4 3.05015
PDIA5 protein disulfide isomerase family A, member 5 2.95805
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.92337
SNAP25 synaptosomal-associated protein, 25kDa 2.86267
WDR76 WD repeat domain 76 2.76955
GTPBP3 GTP binding protein 3 (mitochondrial) 2.52264
NUTF2 nuclear transport factor 2 2.46924
SAC3D1 SAC3 domain containing 1 2.42853
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.40397
NIP7 NIP7, nucleolar pre-rRNA processing protein 2.39878
CBX1 chromobox homolog 1 2.2818
COMP cartilage oligomeric matrix protein 2.25078
SREK1IP1 SREK1-interacting protein 1 2.2437
TBCA tubulin folding cofactor A 2.22375
KPNB1 karyopherin (importin) beta 1 2.13566
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) 2.11455
PI15 peptidase inhibitor 15 2.11328
CEP85 centrosomal protein 85kDa 2.11247
HSF2BP heat shock transcription factor 2 binding protein 2.10971
ORC6 origin recognition complex, subunit 6 2.09438
CNN2 calponin 2 2.08018
CCNE2 cyclin E2 2.05766
GMDS GDP-mannose 4,6-dehydratase 2.0043

decreased expression

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.24904
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.87107
MRPS2 mitochondrial ribosomal protein S2 -3.37954
CDC20 cell division cycle 20 -3.25351
COG7 component of oligomeric golgi complex 7 -3.16041
PARP2 poly (ADP-ribose) polymerase 2 -3.1233
TXNDC9 thioredoxin domain containing 9 -3.08292
PAEP progestagen-associated endometrial protein -2.85243
NT5DC2 5'-nucleotidase domain containing 2 -2.84096
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.78883
UBAC1 UBA domain containing 1 -2.75963
MUC4 mucin 4, cell surface associated -2.6927
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.66233
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.51248
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.46114
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.40602
LPAR6 lysophosphatidic acid receptor 6 -2.39229
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -2.32595
RERGL RERG/RAS-like -2.30629
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.28457
PARM1 prostate androgen-regulated mucin-like protein 1 -2.26897
CCL5 chemokine (C-C motif) ligand 5 -2.26653
METTL17 methyltransferase like 17 -2.25269
STX11 syntaxin 11 -2.24271
AHSP alpha hemoglobin stabilizing protein -2.23879
CD1D CD1d molecule -2.22354
KRT8 keratin 8, type II -2.20609
CRNKL1 crooked neck pre-mRNA splicing factor 1 -2.19542
ARID4B AT rich interactive domain 4B (RBP1-like) -2.1934
RALGDS ral guanine nucleotide dissociation stimulator -2.1866
TENT4A terminal nucleotidyltransferase 4A -2.17789
PLEKHA6 pleckstrin homology domain containing, family A member 6 -2.17527
FECH ferrochelatase -2.16389
DPYD dihydropyrimidine dehydrogenase -2.14897
KDM3A lysine (K)-specific demethylase 3A -2.1457
ANKRD36C ankyrin repeat domain 36C -2.12314
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.1103
ATP4B ATPase, H+/K+ exchanging, beta polypeptide -2.10345
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.09519
HOXD10 homeobox D10 -2.09405
SGK1 serum/glucocorticoid regulated kinase 1 -2.0787
LRRC40 leucine rich repeat containing 40 -2.0736
ALAS2 5'-aminolevulinate synthase 2 -2.06361
SCN2A sodium channel, voltage gated, type II alpha subunit -2.06018
ANXA1 annexin A1 -2.05983
CLN3 ceroid-lipofuscinosis, neuronal 3 -2.05601
ITGA1 integrin, alpha 1 -2.04596
EIF5 eukaryotic translation initiation factor 5 -2.04371
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -2.03659
ARMCX1 armadillo repeat containing, X-linked 1 -2.03525
FBXO21 F-box protein 21 -2.03295
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -2.01774
ANXA2 annexin A2 -2.01271
IL10RA interleukin 10 receptor, alpha -2.01188
NOX4 NADPH oxidase 4 -2.00593
PAGE4 P antigen family, member 4 (prostate associated) -2.00078