CRCGN015_MCF10A.WT.HP_24H:E18 Gene Set
Genes
47 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HMOX1
|
heme oxygenase 1
|
4.49506
|
|
MYLK
|
myosin light chain kinase
|
4.37685
|
|
WIF1
|
WNT inhibitory factor 1
|
4.05316
|
|
TXNRD1
|
thioredoxin reductase 1
|
4.02736
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.38262
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
2.82479
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.81464
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.74881
|
|
ZNF586
|
zinc finger protein 586
|
2.72007
|
|
VGLL4
|
vestigial-like family member 4
|
2.70255
|
|
BLTP2
|
bridge-like lipid transfer protein family member 2
|
2.57337
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.53343
|
|
IDE
|
insulin-degrading enzyme
|
2.35001
|
|
SDF2
|
stromal cell-derived factor 2
|
2.34933
|
|
GSR
|
glutathione reductase
|
2.33813
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.31979
|
|
SQSTM1
|
sequestosome 1
|
2.29457
|
|
FLNA
|
filamin A, alpha
|
2.28389
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.17297
|
|
NUCB2
|
nucleobindin 2
|
2.17032
|
|
SUPT6H
|
suppressor of Ty 6 homolog (S. cerevisiae)
|
2.131
|
|
CNRIP1
|
cannabinoid receptor interacting protein 1
|
2.11235
|
|
EMC3
|
ER membrane protein complex subunit 3
|
2.04424
|
|
ACTG2
|
actin, gamma 2, smooth muscle, enteric
|
2.01891
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
S100A8
|
S100 calcium binding protein A8
|
-4.72036
|
|
TEX10
|
testis expressed 10
|
-4.46225
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.69545
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.35484
|
|
TES
|
testin LIM domain protein
|
-3.31715
|
|
PRKCQ
|
protein kinase C, theta
|
-3.01775
|
|
WASHC4
|
WASH complex subunit 4
|
-2.98738
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
-2.78622
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
-2.7429
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.62455
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.46489
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-2.44006
|
|
SERPINC1
|
serpin peptidase inhibitor, clade C (antithrombin), member 1
|
-2.28086
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.27859
|
|
FBXO21
|
F-box protein 21
|
-2.19296
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
-2.16942
|
|
SERPINA4
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
|
-2.10353
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.10326
|
|
CAB39
|
calcium binding protein 39
|
-2.08033
|
|
TFDP1
|
transcription factor Dp-1
|
-2.06073
|
|
EIF2B1
|
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
|
-2.0239
|
|
RLIG1
|
RNA 5'-phosphate and 3'-OH ligase 1
|
-2.01692
|
|
GDF15
|
growth differentiation factor 15
|
-2.01221
|
