CRCGN015_MCF10A.WT.HP_24H:E20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n??=-diacetylbenzidine 34.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL2 chemokine (C-X-C motif) ligand 2 5.34958
TBX2 T-box 2 4.61916
TCTN1 tectonic family member 1 3.13738
SNAP25 synaptosomal-associated protein, 25kDa 3.09976
HMGA2 high mobility group AT-hook 2 2.65057
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.63002
TNIP1 TNFAIP3 interacting protein 1 2.58965
LOC124907782 dual specificity protein phosphatase 22 2.55691
ATP11B ATPase, class VI, type 11B 2.36531
RPIA ribose 5-phosphate isomerase A 2.24232
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.22315
MTA1 metastasis associated 1 2.19183
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.08514

decreased expression

Symbol Name Standardized Value
ALDOC aldolase C, fructose-bisphosphate -5.02978
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.24385
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.9761
PRR15L proline rich 15-like -2.95212
TOMM70 translocase of outer mitochondrial membrane 70 -2.89549
HSPB1 heat shock 27kDa protein 1 -2.78319
HAT1 histone acetyltransferase 1 -2.75729
CD81 CD81 molecule -2.60577
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.52048
INSIG1 insulin induced gene 1 -2.51617
CREG1 cellular repressor of E1A-stimulated genes 1 -2.45772
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.36312
SESN1 sestrin 1 -2.32447
ECD ecdysoneless homolog (Drosophila) -2.21431
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.09972
ABHD4 abhydrolase domain containing 4 -2.09028
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -2.05565
ARID4B AT rich interactive domain 4B (RBP1-like) -2.04749