CRCGN015_MCF10A.WT.HP_24H:E21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n,n??=-diacetylbenzidine 11.36 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 6.47666
TLR4 toll-like receptor 4 4.1383
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.12771
WIF1 WNT inhibitory factor 1 3.18395
CCR2 chemokine (C-C motif) receptor 2 2.36694
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.32188
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.26633
GPR65 G protein-coupled receptor 65 2.04323
TIAM1 T-cell lymphoma invasion and metastasis 1 2.02876

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -4.44114
ACOT9 acyl-CoA thioesterase 9 -3.87706
HMG20B high mobility group 20B -3.53562
GDF15 growth differentiation factor 15 -3.49496
PTK2 protein tyrosine kinase 2 -3.08993
BASP1 brain abundant, membrane attached signal protein 1 -2.62698
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.57326
SLC35F2 solute carrier family 35, member F2 -2.50608
RGS2 regulator of G-protein signaling 2 -2.4787
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.32967
RAB9A RAB9A, member RAS oncogene family -2.14845