CRCGN015_MCF10A.WT.HP_24H:E23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description norethindrone 33.36 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.53072
PNKP polynucleotide kinase 3'-phosphatase 4.40761
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.09462
CNPY3 canopy FGF signaling regulator 3 3.02439
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.99231
ACAA1 acetyl-CoA acyltransferase 1 2.46355
AURKB aurora kinase B 2.43146
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.32295
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.30041
MDM4 MDM4, p53 regulator 2.27885
COMP cartilage oligomeric matrix protein 2.18721
MTA2 metastasis associated 1 family, member 2 2.16973
WDR76 WD repeat domain 76 2.02614

decreased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.87587
PPIC peptidylprolyl isomerase C (cyclophilin C) -4.34896
BASP1 brain abundant, membrane attached signal protein 1 -4.02843
MSMO1 methylsterol monooxygenase 1 -2.55787
PCCB propionyl CoA carboxylase, beta polypeptide -2.5282
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.26378