CRCGN015_MCF10A.WT.HP_24H:F02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diethylstilbestrol 33.49 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 7.48681
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.04368
CNRIP1 cannabinoid receptor interacting protein 1 3.01942
WIF1 WNT inhibitory factor 1 2.79923
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.76875
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.5819
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.48602
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.44004
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.41992
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.2743
KIF5C kinesin family member 5C 2.16246
HBA1 hemoglobin, alpha 1 2.06699
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 2.02877

decreased expression

Symbol Name Standardized Value
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.56268
PFN1 profilin 1 -3.3682
RNF167 ring finger protein 167 -3.26688
KIF14 kinesin family member 14 -3.22061
ALDOC aldolase C, fructose-bisphosphate -3.11466
GDF15 growth differentiation factor 15 -3.00444
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.66546
CCDC86 coiled-coil domain containing 86 -2.65355
PRR15L proline rich 15-like -2.62437
TSPAN4 tetraspanin 4 -2.51725
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.45327
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.38809
WASHC4 WASH complex subunit 4 -2.3013
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 -2.16894
ADRB2 adrenoceptor beta 2, surface -2.16715
SMC1A structural maintenance of chromosomes 1A -2.15557
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -2.0953
RPA3 replication protein A3, 14kDa -2.00225