CRCGN015_MCF10A.WT.HP_24H:F05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K63993117 34.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 5.69801
WIF1 WNT inhibitory factor 1 5.01725
PDIA5 protein disulfide isomerase family A, member 5 4.55602
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.00504
TPD52L2 tumor protein D52-like 2 2.76588
CERK ceramide kinase 2.63971
MSRA methionine sulfoxide reductase A 2.59178
STMN2 stathmin 2 2.4504
LSR lipolysis stimulated lipoprotein receptor 2.20534
NSG2 neuronal vesicle trafficking associated 2 2.16586
AGR2 anterior gradient 2 2.06659

decreased expression

Symbol Name Standardized Value
PGAM4 phosphoglycerate mutase family member 4 -4.77123
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.32247
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.84262
SGK1 serum/glucocorticoid regulated kinase 1 -2.87378
S100A8 S100 calcium binding protein A8 -2.79484
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -2.48825
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 -2.39004
COPS7A COP9 signalosome subunit 7A -2.18019
GPR87 G protein-coupled receptor 87 -2.13358
GDF15 growth differentiation factor 15 -2.12329
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase -2.11846
IL23A interleukin 23, alpha subunit p19 -2.11765
UPK2 uroplakin 2 -2.08902
PADI3 peptidyl arginine deiminase, type III -2.06767
CBR3 carbonyl reductase 3 -2.06732
ZBTB5 zinc finger and BTB domain containing 5 -2.05842
CCDC88C coiled-coil domain containing 88C -2.03007
KERA keratocan -2.00135