CRCGN015_MCF10A.WT.HP_24H:F06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K63993117 11.39 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MMP1 matrix metallopeptidase 1 3.44572
SNAP25 synaptosomal-associated protein, 25kDa 3.29817
CCL2 chemokine (C-C motif) ligand 2 3.15198
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.73585
SPAG4 sperm associated antigen 4 2.3489
ACAA1 acetyl-CoA acyltransferase 1 2.29571
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.21797
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.18401
PKN1 protein kinase N1 2.17022
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.13625
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 2.08418

decreased expression

Symbol Name Standardized Value
MALT1 MALT1 paracaspase -3.2798
REEP5 receptor accessory protein 5 -2.99401
YME1L1 YME1-like 1 ATPase -2.71332
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.50423
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.43673
CORO1A coronin, actin binding protein, 1A -2.31611
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.295
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.2223