CRCGN015_MCF10A.WT.HP_24H:F07 Gene Set
Genes
38 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
4.75359
|
|
E2F2
|
E2F transcription factor 2
|
4.66302
|
|
ZW10
|
zw10 kinetochore protein
|
3.4903
|
|
SNX11
|
sorting nexin 11
|
3.19753
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.93924
|
|
RFC5
|
replication factor C (activator 1) 5, 36.5kDa
|
2.81486
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.49462
|
|
NT5M
|
5',3'-nucleotidase, mitochondrial
|
2.43109
|
|
BARD1
|
BRCA1 associated RING domain 1
|
2.22355
|
|
COX6A1
|
cytochrome c oxidase subunit VIa polypeptide 1
|
2.18663
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.17909
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.10135
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
2.10083
|
|
PPP1CC
|
protein phosphatase 1, catalytic subunit, gamma isozyme
|
2.08681
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.06686
|
|
EXOSC9
|
exosome component 9
|
2.05025
|
|
XPO4
|
exportin 4
|
2.01735
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.25067
|
|
GDF15
|
growth differentiation factor 15
|
-5.17068
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.88206
|
|
CDC25B
|
cell division cycle 25B
|
-4.76475
|
|
TIMP1
|
TIMP metallopeptidase inhibitor 1
|
-4.5207
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.6667
|
|
HTRA1
|
HtrA serine peptidase 1
|
-3.08787
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
-2.84674
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.67199
|
|
PPP1R26
|
protein phosphatase 1, regulatory subunit 26
|
-2.50431
|
|
COQ4
|
coenzyme Q4
|
-2.47345
|
|
TSC1
|
tuberous sclerosis 1
|
-2.40452
|
|
MVP
|
major vault protein
|
-2.39382
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
-2.36475
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-2.23599
|
|
CEMIP
|
cell migration inducing protein, hyaluronan binding
|
-2.21694
|
|
SGK1
|
serum/glucocorticoid regulated kinase 1
|
-2.1499
|
|
CENPB
|
centromere protein B, 80kDa
|
-2.13602
|
|
THBS2
|
thrombospondin 2
|
-2.13131
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.10836
|
|
RIDA
|
reactive intermediate imine deaminase A homolog
|
-2.09007
|
