CRCGN015_MCF10A.WT.HP_24H:F11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description cyclohexylamine.hcl 33.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 5.09998
ADGRE5 adhesion G protein-coupled receptor E5 2.98442
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.46745
COPS7A COP9 signalosome subunit 7A 2.44008
THYN1 thymocyte nuclear protein 1 2.35732
WIF1 WNT inhibitory factor 1 2.17687
EPN2 epsin 2 2.14504
CGRRF1 cell growth regulator with ring finger domain 1 2.11628
ACAA1 acetyl-CoA acyltransferase 1 2.00491

decreased expression

Symbol Name Standardized Value
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -5.87177
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -4.68833
ISOC1 isochorismatase domain containing 1 -4.10914
GDF15 growth differentiation factor 15 -3.53445
CCNB1 cyclin B1 -3.28336
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.25891
HAT1 histone acetyltransferase 1 -3.12553
ANXA2 annexin A2 -3.03836
PRPF4 pre-mRNA processing factor 4 -2.97968
TCTA T-cell leukemia translocation altered -2.58757
RXYLT1 ribitol xylosyltransferase 1 -2.47613
LYPLA1 lysophospholipase I -2.09129
IRF2BP1 interferon regulatory factor 2 binding protein 1 -2.06742
DLX2 distal-less homeobox 2 -2.0568
LINC02762 long intergenic non-protein coding RNA 2762 -2.04111
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -2.00544
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.00313