CRCGN015_MCF10A.WT.HP_24H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description caffeic-acid 32.81 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.44935
GATA3 GATA binding protein 3 4.34964
MAP7 microtubule-associated protein 7 4.27264
SNX11 sorting nexin 11 4.2655
CARMIL1 capping protein regulator and myosin 1 linker 1 3.62176
GSTZ1 glutathione S-transferase zeta 1 3.0336
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.97012
FPGS folylpolyglutamate synthase 2.5638
HBA1 hemoglobin, alpha 1 2.44609
NFE2L1 nuclear factor, erythroid 2-like 1 2.13656
ADGRE5 adhesion G protein-coupled receptor E5 2.08623

decreased expression

Symbol Name Standardized Value
CHIC2 cysteine-rich hydrophobic domain 2 -4.78076
NLRP4 NLR family, pyrin domain containing 4 -4.09226
RPIA ribose 5-phosphate isomerase A -3.38119
HSPA1A heat shock 70kDa protein 1A -2.55807
RNF167 ring finger protein 167 -2.54788
DERA deoxyribose-phosphate aldolase (putative) -2.49031
NUP93 nucleoporin 93kDa -2.47445
ENOPH1 enolase-phosphatase 1 -2.42627
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.04362
FAIM Fas apoptotic inhibitory molecule -2.02685
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae) -2.02143