CRCGN015_MCF10A.WT.HP_24H:F21 Gene Set
Genes
40 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
6.0413
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
5.15057
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.56717
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.32053
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.30768
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.25547
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
2.60633
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.59441
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.58532
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.5834
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.47188
|
|
BARD1
|
BRCA1 associated RING domain 1
|
2.28946
|
|
KLHL36
|
kelch-like family member 36
|
2.24429
|
|
BLMH
|
bleomycin hydrolase
|
2.22776
|
|
GRAMD1B
|
GRAM domain containing 1B
|
2.15876
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.12887
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.12217
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.1212
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RNF167
|
ring finger protein 167
|
-5.90049
|
|
MSN
|
moesin
|
-5.45167
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-4.25195
|
|
DNM1L
|
dynamin 1-like
|
-4.03035
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.93139
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.90829
|
|
CD44
|
CD44 molecule (Indian blood group)
|
-3.87239
|
|
CYCS
|
cytochrome c, somatic
|
-3.8467
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-3.49462
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
-3.45451
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.13247
|
|
PTK2
|
protein tyrosine kinase 2
|
-2.90034
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
-2.74682
|
|
PPARGC1A
|
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
|
-2.27733
|
|
CYP27B1
|
cytochrome P450, family 27, subfamily B, polypeptide 1
|
-2.2079
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
-2.14321
|
|
MUL1
|
mitochondrial E3 ubiquitin protein ligase 1
|
-2.0898
|
|
PLAGL1
|
pleiomorphic adenoma gene-like 1
|
-2.08052
|
|
CSRNP2
|
cysteine-serine-rich nuclear protein 2
|
-2.02888
|
|
MFAP4
|
microfibrillar-associated protein 4
|
-2.02525
|
|
KATNBL1
|
katanin p80 subunit B-like 1
|
-2.00599
|
|
ERGIC2
|
ERGIC and golgi 2
|
-2.00311
|
