CRCGN015_MCF10A.WT.HP_24H:F22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 100.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.32088
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.20641
KDM5A lysine (K)-specific demethylase 5A 3.73062
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.86784
COMP cartilage oligomeric matrix protein 2.58614
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.58219
CXCR4 chemokine (C-X-C motif) receptor 4 2.52852
ACAA1 acetyl-CoA acyltransferase 1 2.52639
COQ8A coenzyme Q8A 2.28725
POMZP3 POM121 and ZP3 fusion 2.22081
NRBF2 nuclear receptor binding factor 2 2.09787

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.60997
GDF15 growth differentiation factor 15 -3.22235
HMG20B high mobility group 20B -3.15194
SCYL3 SCY1-like 3 (S. cerevisiae) -2.95136
HSPA8 heat shock 70kDa protein 8 -2.94767
NPDC1 neural proliferation, differentiation and control, 1 -2.765
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.50113
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.42539