CRCGN015_MCF10A.WT.HP_24H:F24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1h-1,2,3-benzotriazole 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

32 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:F24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 4.30642
ADGRE5 adhesion G protein-coupled receptor E5 4.28374
NOTCH1 notch 1 3.25508
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.19766
CCL2 chemokine (C-C motif) ligand 2 2.93894
MAMLD1 mastermind-like domain containing 1 2.84653
GARRE1 granule associated Rac and RHOG effector 1 2.75163
EML3 echinoderm microtubule associated protein like 3 2.63552
KLHL9 kelch-like family member 9 2.5515
DNM1 dynamin 1 2.42014
ANAPC2 anaphase promoting complex subunit 2 2.35763
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.31361
PNPLA6 patatin-like phospholipase domain containing 6 2.21933
UBQLN2 ubiquilin 2 2.21584
MAGEF1 melanoma antigen family F1 2.17333
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 2.12122
MELK maternal embryonic leucine zipper kinase 2.08858
EMD emerin 2.04278
FAM193B family with sequence similarity 193, member B 2.00526

decreased expression

Symbol Name Standardized Value
DNM1L dynamin 1-like -3.97268
MTERF3 mitochondrial transcription termination factor 3 -3.87481
PUF60 poly-U binding splicing factor 60KDa -3.86039
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.76908
HEATR1 HEAT repeat containing 1 -3.65687
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.21821
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.94884
SCYL3 SCY1-like 3 (S. cerevisiae) -2.54326
BMAL2 basic helix-loop-helix ARNT like 2 -2.24515
FOSL1 FOS-like antigen 1 -2.23238
BASP1 brain abundant, membrane attached signal protein 1 -2.21498
SCYL2 SCY1-like 2 (S. cerevisiae) -2.04793
ELOC elongin C -2.02482