CRCGN015_MCF10A.WT.HP_24H:G02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nifedipine 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.20543
MPC2 mitochondrial pyruvate carrier 2 2.69398
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.60732
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.41994
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.36035
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.09941

decreased expression

Symbol Name Standardized Value
RPIA ribose 5-phosphate isomerase A -3.87639
GDF15 growth differentiation factor 15 -3.80623
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -3.00334
ALDOC aldolase C, fructose-bisphosphate -2.68646
TUBB6 tubulin, beta 6 class V -2.61243
FAIM Fas apoptotic inhibitory molecule -2.57581
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.53254
MCM3 minichromosome maintenance complex component 3 -2.44226
MTERF3 mitochondrial transcription termination factor 3 -2.28687