| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | nifedipine 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAMLD1 | mastermind-like domain containing 1 | 5.04231 |
| AGR2 | anterior gradient 2 | 4.91571 |
| AXIN1 | axin 1 | 4.84559 |
| COMP | cartilage oligomeric matrix protein | 4.84556 |
| HBA1 | hemoglobin, alpha 1 | 4.5742 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.40477 |
| VGLL4 | vestigial-like family member 4 | 3.52704 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 3.23123 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 3.22672 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 3.08837 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.05119 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.98504 |
| ESYT1 | extended synaptotagmin-like protein 1 | 2.5248 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 2.51033 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 2.41195 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 2.41103 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 2.2627 |
| OLFML2B | olfactomedin-like 2B | 2.20427 |
| RBM12B | RNA binding motif protein 12B | 2.19582 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.19504 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 2.19075 |
| TBX2 | T-box 2 | 2.18898 |
| MAPK1 | mitogen-activated protein kinase 1 | 2.04597 |
| RAB23 | RAB23, member RAS oncogene family | 2.04565 |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 | 2.04466 |
| TENT5A | terminal nucleotidyltransferase 5A | 2.02574 |
| ANKRD28 | ankyrin repeat domain 28 | 2.02076 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 2.00105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MSN | moesin | -4.64566 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.46272 |
| PCNA | proliferating cell nuclear antigen | -4.41304 |
| KIF14 | kinesin family member 14 | -4.35557 |
| BAG3 | BCL2-associated athanogene 3 | -4.32073 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -4.12758 |
| RBM34 | RNA binding motif protein 34 | -3.41504 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -3.3661 |
| TMEM230 | transmembrane protein 230 | -2.90336 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.66907 |
| PFN1 | profilin 1 | -2.54782 |
| STXBP2 | syntaxin binding protein 2 | -2.51788 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.38661 |
| PTK2 | protein tyrosine kinase 2 | -2.17323 |
| MCM6 | minichromosome maintenance complex component 6 | -2.17282 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.16853 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -2.16091 |
| KIF16B | kinesin family member 16B | -2.14709 |
| CD81 | CD81 molecule | -2.13106 |
| ZNF532 | zinc finger protein 532 | -2.08642 |
| SALL1 | spalt-like transcription factor 1 | -2.08148 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | -2.07858 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -2.07096 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -2.06636 |
| SLC25A44 | solute carrier family 25, member 44 | -2.06635 |
| PANK2 | pantothenate kinase 2 | -2.04348 |
| DDRGK1 | DDRGK domain containing 1 | -2.03552 |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 | -2.02809 |
