CRCGN015_MCF10A.WT.HP_24H:G08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-chloroacetophenone 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.34567
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.11314
ANO10 anoctamin 10 4.06578
TBX2 T-box 2 3.64318
AGR2 anterior gradient 2 2.6249
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.5764
WIF1 WNT inhibitory factor 1 2.45783
RPP38 ribonuclease P/MRP 38kDa subunit 2.45751
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 2.01604
SYNGAP1 synaptic Ras GTPase activating protein 1 2.01245

decreased expression

Symbol Name Standardized Value
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.12567
TES testin LIM domain protein -3.93553
TUBB6 tubulin, beta 6 class V -3.2239
ADI1 acireductone dioxygenase 1 -3.15218
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.05737
LYPLA1 lysophospholipase I -2.92528
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.90024
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.76724
VAT1 vesicle amine transport 1 -2.70098
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.55987
PRPF4 pre-mRNA processing factor 4 -2.52857
RGS2 regulator of G-protein signaling 2 -2.4986
ATP11B ATPase, class VI, type 11B -2.40173
NR0B2 nuclear receptor subfamily 0, group B, member 2 -2.03396
FGF9 fibroblast growth factor 9 -2.02502
CBY1 chibby homolog 1 (Drosophila) -2.01672