CRCGN015_MCF10A.WT.HP_24H:G10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 105.01 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FGFR4 fibroblast growth factor receptor 4 7.65996
COMP cartilage oligomeric matrix protein 5.1068
PRAF2 PRA1 domain family, member 2 4.59489
PNKP polynucleotide kinase 3'-phosphatase 4.40361
EAPP E2F-associated phosphoprotein 4.23724
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 4.12371
AKT1 v-akt murine thymoma viral oncogene homolog 1 4.07401
E2F2 E2F transcription factor 2 3.9052
KDM5A lysine (K)-specific demethylase 5A 3.62652
MAST2 microtubule associated serine/threonine kinase 2 3.35107
SPTSSA serine palmitoyltransferase, small subunit A 3.2706
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.26329
SRP54 signal recognition particle 54kDa 2.59941
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 2.54723
MEN1 multiple endocrine neoplasia I 2.49443
GLB1L2 galactosidase, beta 1-like 2 2.48682
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.47743
TBC1D15 TBC1 domain family, member 15 2.45576
PRORP protein only RNase P catalytic subunit 2.42653
FBXL2 F-box and leucine-rich repeat protein 2 2.36306
DAO D-amino-acid oxidase 2.3235
FAM149A family with sequence similarity 149, member A 2.30938
PTCD1 pentatricopeptide repeat domain 1 2.30914
SART1 squamous cell carcinoma antigen recognized by T cells 2.28789
ATG2A autophagy related 2A 2.28361
BIK BCL2-interacting killer (apoptosis-inducing) 2.26319
TRAPPC4 trafficking protein particle complex 4 2.2187
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.20841
XPC xeroderma pigmentosum, complementation group C 2.19913
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 2.14049
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 2.11177
BAZ1A bromodomain adjacent to zinc finger domain, 1A 2.10462
SHPK sedoheptulokinase 2.07796
TWSG1 twisted gastrulation BMP signaling modulator 1 2.06737
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 2.06538
COL11A1 collagen, type XI, alpha 1 2.05771
TMEM260 transmembrane protein 260 2.03912
ACAD8 acyl-CoA dehydrogenase family, member 8 2.03909
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 2.03618
SLC16A6 solute carrier family 16, member 6 2.03472
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 2.03371
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 2.01493

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -4.88497
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.77208
DSG2 desmoglein 2 -4.38157
ARPP19 cAMP-regulated phosphoprotein, 19kDa -4.29871
ANO3 anoctamin 3 -2.74868
MSN moesin -2.64675
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -2.52744
SUCO SUN domain containing ossification factor -2.45314
PRKCB protein kinase C, beta -2.43319
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.42943
MAPK6 mitogen-activated protein kinase 6 -2.419
RBM34 RNA binding motif protein 34 -2.35316
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -2.32754
MCM3 minichromosome maintenance complex component 3 -2.30621
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -2.28332
TMOD1 tropomodulin 1 -2.26601
HPCA hippocalcin -2.24232
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -2.23565
RPL35 ribosomal protein L35 -2.21365
CANT1 calcium activated nucleotidase 1 -2.17367
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -2.17362
ACYP2 acylphosphatase 2, muscle type -2.1464
WASF2 WAS protein family, member 2 -2.1439
CDC42SE1 CDC42 small effector 1 -2.13477
NCF2 neutrophil cytosolic factor 2 -2.12088
EIF3H eukaryotic translation initiation factor 3, subunit H -2.111
MMD monocyte to macrophage differentiation-associated -2.09853
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.07867
MTERF3 mitochondrial transcription termination factor 3 -2.05708
SV2C synaptic vesicle glycoprotein 2C -2.04468
SUB1 SUB1 homolog (S. cerevisiae) -2.03296