CRCGN015_MCF10A.WT.HP_24H:G11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosopyrrolidine 35.0 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

22 genes differentially expressed following the CRCGN015_MCF10A.WT.HP_24H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FKBP14 FK506 binding protein 14, 22 kDa 4.8424
MAMLD1 mastermind-like domain containing 1 4.23833
KLHL9 kelch-like family member 9 3.13789
COL11A1 collagen, type XI, alpha 1 3.05069
HBA1 hemoglobin, alpha 1 2.56759
NELFE negative elongation factor complex member E 2.43477
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.42502
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.39578
COG2 component of oligomeric golgi complex 2 2.1173
GUK1 guanylate kinase 1 2.02066

decreased expression

Symbol Name Standardized Value
DIPK1A divergent protein kinase domain 1A -4.95862
HSPA8 heat shock 70kDa protein 8 -4.86027
OXA1L oxidase (cytochrome c) assembly 1-like -4.35995
PCNA proliferating cell nuclear antigen -4.33613
MTERF3 mitochondrial transcription termination factor 3 -2.84741
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.77887
KRT14 keratin 14, type I -2.64931
TMEM230 transmembrane protein 230 -2.535
CENPB centromere protein B, 80kDa -2.30794
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.1934
FKBP1C FK506 binding protein 1C -2.13813
PANK2 pantothenate kinase 2 -2.06103